2-(benzoylamino)-3-[[7[[(2R)-2-(benzoylamino)-3-methoxy-3-oxopropyl]thio]-1,7-bis(4,5-dimethoxy-2-nitrophenyl)heptyl]thio]-(2R)-propanoic acid methyl ester

Base Information

• Chemical Name: 2-(benzoylamino)-3-[[7[[(2R)-2-(benzoylamino)-3-methoxy-3-oxopropyl]thio]-1,7-bis(4,5-dimethoxy-2-nitrophenyl)heptyl]thio]-(2R)-propanoic acid methyl ester
• CAS No.: 1159498-13-1
• Molecular Formula: C₄₅H₅₂N₄O₁₄S₂
• Molecular Weight: 937.058
• Mol file: 1159498-13-1.mol

Synonyms:

Chemical Property of 2-(benzoylamino)-3-[[7[[(2R)-2-(benzoylamino)-3-methoxy-3-oxopropyl]thio]-1,7-bis(4,5-dimethoxy-2-nitrophenyl)heptyl]thio]-(2R)-propanoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(benzoylamino)-3-[[7[[(2R)-2-(benzoylamino)-3-methoxy-3-oxopropyl]thio]-1,7-bis(4,5-dimethoxy-2-nitrophenyl)heptyl]thio]-(2R)-propanoic acid methyl ester

There total 1 articles about 2-(benzoylamino)-3-[[7[[(2R)-2-(benzoylamino)-3-methoxy-3-oxopropyl]thio]-1,7-bis(4,5-dimethoxy-2-nitrophenyl)heptyl]thio]-(2R)-propanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

1-[1,7-dibromo-7-(4,5-dimethoxy-2-nitrophenyl)heptyl]-4,5-dimethoxy-2-nitro-benzene (1159498-08-4) + N-benzoyl-L-cysteine dimethyl ester (5673-89-2) → 2-(benzoylamino)-3-[[7[[(2R)-2-(benzoylamino)-3-methoxy-3-oxopropyl]thio]-1,7-bis(4,5-dimethoxy-2-nitrophenyl)heptyl]thio]-(2R)-propanoic acid methyl ester (1159498-13-1)

Guidance literature:

With sodium hydrogencarbonate; In methanol; Inert atmosphere;

DOI:10.1016/j.tetlet.2009.03.009

Reference yield:

2-(benzoylamino)-3-[[7[[(2R)-2-(benzoylamino)-3-methoxy-3-oxopropyl]thio]-1,7-bis(4,5-dimethoxy-2-nitrophenyl)heptyl]thio]-(2R)-propanoic acid methyl ester (1159498-13-1) → N-benzoyl-L-cysteine dimethyl ester (5673-89-2)

Guidance literature:

With water; D,L-dithiothreitol; In ethanol; phosohate buffer; pH=7.3; Time; Reactivity; Quantum yield; Photolysis;

DOI:10.1016/j.tetlet.2009.03.009

upstream raw materials:

1-[1,7-dibromo-7-(4,5-dimethoxy-2-nitrophenyl)heptyl]-4,5-dimethoxy-2-nitro-benzene

N-benzoyl-L-cysteine dimethyl ester

Downstream raw materials:

N-benzoyl-L-cysteine dimethyl ester