exo-1-Brom-1a,2,3,7b-tetrahydro-exo-2-phenyl-1H-cyclopropanaphthalin

• Chemical Name: exo-1-Brom-1a,2,3,7b-tetrahydro-exo-2-phenyl-1H-cyclopropanaphthalin
• Molecular Formula: C₁₇H₁₅Br
• Molecular Weight: 299.21
• Mol file: 138153-12-5.mol

Synonyms:

Chemical Property of exo-1-Brom-1a,2,3,7b-tetrahydro-exo-2-phenyl-1H-cyclopropa

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of exo-1-Brom-1a,2,3,7b-tetrahydro-exo-2-phenyl-1H-cyclopropa

There total 2 articles about exo-1-Brom-1a,2,3,7b-tetrahydro-exo-2-phenyl-1H-cyclopropanaphthalin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

1,1-Dibrom-1a,2,3,7b-tetrahydro-exo-2-phenyl-1H-cyclopropanaphthalin (138153-11-4) → exo-1-Brom-1a,2,3,7b-tetrahydro-exo-2-phenyl-1H-cyclopropanaphthalin (138153-12-5) + 1,2,3,4-Tetrahydro-3-phenyl-1,2,3-methenonaphthalin (138089-62-0)

Guidance literature:

With methyllithium; In diethyl ether; at 0 ℃; for 0.75h;

Reference yield:

2-phenyl-1,2-dihydronaphthalene (62019-39-0) → exo-1-Brom-1a,2,3,7b-tetrahydro-exo-2-phenyl-1H-cyclopropanaphthalin (138153-12-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 35 percent / 50percent NaOH, tri-n-butylamine / CH₂Cl₂ / 7 h / 40 °C

2: 1.4 percent / CH₃Li / various solvent(s); diethyl ether / 0.75 h / 0 °C

With sodium hydroxide; tributyl-amine; methyllithium; In diethyl ether; dichloromethane;

upstream raw materials:

1,1-Dibrom-1a,2,3,7b-tetrahydro-exo-2-phenyl-1H-cyclopropanaphthalin

2-phenyl-1,2-dihydronaphthalene