(R)-3-Tetradecanoyloxy-tetradecanoic acid (2R,3S,4R,5R)-2-benzyloxycarbonyloxymethyl-3-(diphenoxy-phosphoryloxy)-6-(2,2,2-trichloro-acetimidoyloxy)-5-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-4-yl ester

Base Information

Chemical Name:(R)-3-Tetradecanoyloxy-tetradecanoic acid (2R,3S,4R,5R)-2-benzyloxycarbonyloxymethyl-3-(diphenoxy-phosphoryloxy)-6-(2,2,2-trichloro-acetimidoyloxy)-5-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-4-yl ester
CAS No.:214051-03-3
Molecular Formula:C₅₉H₈₁Cl₆N₂O₁₅P
Molecular Weight:1301.99
Hs Code.:

(R)-3-Tetradecanoyloxy-tetradecanoic acid (2R,3S,4R,5R)-2-benzyloxycarbonyloxymethyl-3-(diphenoxy-phosphoryloxy)-6-(2,2,2-trichloro-acetimidoyloxy)-5-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-4-yl ester

Synonyms:

Suppliers and Price of (R)-3-Tetradecanoyloxy-tetradecanoic acid (2R,3S,4R,5R)-2-benzyloxycarbonyloxymethyl-3-(diphenoxy-phosphoryloxy)-6-(2,2,2-trichloro-acetimidoyloxy)-5-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-4-yl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-3-Tetradecanoyloxy-tetradecanoic acid (2R,3S,4R,5R)-2-benzyloxycarbonyloxymethyl-3-(diphenoxy-phosphoryloxy)-6-(2,2,2-trichloro-acetimidoyloxy)-5-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-4-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-3-Tetradecanoyloxy-tetradecanoic acid (2R,3S,4R,5R)-2-benzyloxycarbonyloxymethyl-3-(diphenoxy-phosphoryloxy)-6-(2,2,2-trichloro-acetimidoyloxy)-5-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-4-yl ester

There total 5 articles about (R)-3-Tetradecanoyloxy-tetradecanoic acid (2R,3S,4R,5R)-2-benzyloxycarbonyloxymethyl-3-(diphenoxy-phosphoryloxy)-6-(2,2,2-trichloro-acetimidoyloxy)-5-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-4-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 545-06-2
trichloroacetonitrile

: 6-O-benzyloxycarbonyl-2-deoxy-4-O-diphenylphosphono-3-O-[(R)-3-(tetradecanoyloxy)tetradecanoyl]-2-(2,2,2-trichloroethoxycarbonylamino)-D-glucopyranose

: 214051-03-3
(R)-3-Tetradecanoyloxy-tetradecanoic acid (2R,3S,4R,5R)-2-benzyloxycarbonyloxymethyl-3-(diphenoxy-phosphoryloxy)-6-(2,2,2-trichloro-acetimidoyloxy)-5-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-4-yl ester

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 0 ℃; for 0.5h;
DOI:10.1016/S0040-4020(00)00684-0

Reference yield:

: 97562-25-9
allyl 2-deoxy-3-O-<(R)-3-tetradecanoyloxytetradecanoyl>-2-(2,2,2-trichloroethoxycarbonylamino)-α-D-glucopyranoside

: 214051-03-3
(R)-3-Tetradecanoyloxy-tetradecanoic acid (2R,3S,4R,5R)-2-benzyloxycarbonyloxymethyl-3-(diphenoxy-phosphoryloxy)-6-(2,2,2-trichloro-acetimidoyloxy)-5-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-4-yl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: 60 percent / pyridine / pyridine / 2 h / 20 °C

2.1: 98 percent / DMAP / CH₂Cl₂ / 2 h / 20 °C

3.1: [Ir(COD)2(PMePh₂)2]PF₆; H₂ / tetrahydrofuran / 1 h / 20 °C

3.2: 77 percent / H₂O; I₂ / tetrahydrofuran / 1 h / 60 °C

4.1: DBU / CH₂Cl₂ / 0.5 h / 0 °C

With pyridine; dmap; (1,5-cyclooctadiene)[bis(methyldiphenylphosphine)]iridium(I) hexafluorophosphate; hydrogen; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; pyridine; dichloromethane; 1.1: Condensation / 2.1: Condensation / 3.1: Substitution / 3.2: Hydrolysis / 4.1: Addition;
DOI:10.1016/S0040-4020(00)00684-0

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 214051-03-3
(R)-3-Tetradecanoyloxy-tetradecanoic acid (2R,3S,4R,5R)-2-benzyloxycarbonyloxymethyl-3-(diphenoxy-phosphoryloxy)-6-(2,2,2-trichloro-acetimidoyloxy)-5-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-4-yl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: 60 percent / pyridine / pyridine / 2 h / 20 °C

2.1: 98 percent / DMAP / CH₂Cl₂ / 2 h / 20 °C

3.1: [Ir(COD)2(PMePh₂)2]PF₆; H₂ / tetrahydrofuran / 1 h / 20 °C

3.2: 77 percent / H₂O; I₂ / tetrahydrofuran / 1 h / 60 °C

4.1: DBU / CH₂Cl₂ / 0.5 h / 0 °C

With pyridine; dmap; (1,5-cyclooctadiene)[bis(methyldiphenylphosphine)]iridium(I) hexafluorophosphate; hydrogen; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; pyridine; dichloromethane; 1.1: Condensation / 2.1: Condensation / 3.1: Substitution / 3.2: Hydrolysis / 4.1: Addition;
DOI:10.1016/S0040-4020(00)00684-0