C₁₅H₁₃ClO₂

Base Information

• Chemical Name: C₁₅H₁₃ClO₂
• CAS No.: 1372178-20-5
• Molecular Formula: C₁₅H₁₃ClO₂
• Molecular Weight: 260.72
• Mol file: 1372178-20-5.mol

Synonyms:

Chemical Property of C₁₅H₁₃ClO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₅H₁₃ClO₂

There total 1 articles about C₁₅H₁₃ClO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-chloro-4-methylphenol (615-62-3) + 3-Methylbenzoyl chloride (1711-06-4) → C15H13ClO2 (1372178-20-5)

Guidance literature:

DOI:10.1248/cpb.59.1268

Reference yield:

ethyl 3-(chloroformyl)propionate (14794-31-1,97900-84-0) + C15H13ClO2 (1372178-20-5) → C21H21ClO5

Guidance literature:

With triethylamine; In tetrahydrofuran; at 0 ℃; for 1h;

DOI:10.1248/cpb.59.1268

Reference yield:

C15H13ClO2 (1372178-20-5) → C19H14Cl2O3

Guidance literature:

Multi-step reaction with 4 steps

1: triethylamine / tetrahydrofuran / 1 h / 0 °C

2: 1,8-diazabicyclo[5.4.0]undec-7-ene / toluene / 2.5 h / Reflux

3: hydrogenchloride; water; acetic acid / 1 h / Reflux

4: oxalyl dichloride; N,N-dimethyl-formamide / tetrahydrofuran / 0.5 h / 20 °C

With hydrogenchloride; oxalyl dichloride; water; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; N,N-dimethyl-formamide; In tetrahydrofuran; toluene;

DOI:10.1248/cpb.59.1268

upstream raw materials:

3-chloro-4-methylphenol

3-Methylbenzoyl chloride

Downstream raw materials:

C₂₁H₁₉ClO₄