C₁₉H₂₈I₂N₂O₄

Base Information

• Chemical Name: C₁₉H₂₈I₂N₂O₄
• CAS No.: 1167413-22-0
• Molecular Formula: C₁₉H₂₈I₂N₂O₄
• Molecular Weight: 602.251
• Mol file: 1167413-22-0.mol

Synonyms:

Chemical Property of C₁₉H₂₈I₂N₂O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₉H₂₈I₂N₂O₄

There total 4 articles about C₁₉H₂₈I₂N₂O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C19H30N2O4 (1562031-09-7) → C19H28I2N2O4 (1167413-22-0)

Guidance literature:

C₁₉H₃₀N₂O₄; With sodium periodate; acetic acid; sodium chloride; In water; at 20 ℃; for 0.25h;

With potassium iodide; In water; at 0 - 20 ℃;

DOI:10.1021/ma402123w

Reference yield:

N-(tert-butoxycarbonyl)-D-(4-hydroxyphenyl)glycine (27460-85-1) → C19H28I2N2O4 (1167413-22-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride / ethyl acetate / 0 - 20 °C

2.1: sodium periodate; sodium chloride; acetic acid / water / 0.25 h / 20 °C

2.2: 0 - 20 °C

With sodium periodate; acetic acid; 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; sodium chloride; In water; ethyl acetate;

DOI:10.1021/ma402123w

Reference yield:

D-4-hydroxyphenylglycine (22818-40-2) → C19H28I2N2O4 (1167413-22-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium carbonate / water; 1,4-dioxane / 0 - 20 °C

2.1: 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride / ethyl acetate / 0 - 20 °C

3.1: sodium periodate; sodium chloride; acetic acid / water / 0.25 h / 20 °C

3.2: 0 - 20 °C

With sodium periodate; sodium carbonate; acetic acid; 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; sodium chloride; In 1,4-dioxane; water; ethyl acetate;

DOI:10.1021/ma402123w

upstream raw materials:

di-tert-butyl dicarbonate

C₁₉H₃₀N₂O₄

N-(tert-butoxycarbonyl)-D-(4-hydroxyphenyl)glycine

D-4-hydroxyphenylglycine

Downstream raw materials:

3',5'-diiodo-4'-methoxy-N-α-tert-butoxycarbonyl-D-phenylglycine hexylamide