dansyltriphenylphosphonium methylide

Base Information

• Chemical Name: dansyltriphenylphosphonium methylide
• CAS No.: 76631-27-1
• Molecular Formula: C₃₁H₂₈NO₂PS
• Molecular Weight: 509.609
• Mol file: 76631-27-1.mol

Synonyms:

Chemical Property of dansyltriphenylphosphonium methylide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dansyltriphenylphosphonium methylide

There total 1 articles about dansyltriphenylphosphonium methylide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-(dimethylamino)-1-naphthalenesulfonyl fluoride (34523-28-9) + Methylenetriphenylphosphorane (19493-09-5) → dansyltriphenylphosphonium methylide (76631-27-1)

Guidance literature:

In tetrahydrofuran; 1.) -78 deg C, 1 h, 2.) room temp., 0.5 h;

DOI:10.1021/jo00322a029

Reference yield:

dansyltriphenylphosphonium methylide (76631-27-1) → p-nitrophenyl (dansyldiazomethyl)methylphosphinate (76631-30-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 68 percent / p-carboxylbenzenesulfonyl azide / CH₂Cl₂ / 1 h / 0 °C

2: CH₂Cl₂ / 1.) -78 deg C, 2.) room temp., 10 min

3: 1.) -78 deg C, 2.) room temp., 10 min

With p-carboxybenzenesulfonyl azide; In dichloromethane;

DOI:10.1021/jo00322a029

upstream raw materials:

5-(dimethylamino)-1-naphthalenesulfonyl fluoride

Methylenetriphenylphosphorane

Downstream raw materials:

p-nitrophenyl (dansyldiazomethyl)methylphosphinate