(<(tetrahydro-3'',4'',5'',6''-2''H-pyranyl-2)oxy>-2'-ethyl)-6-tetratosyl-1,4,8,11-tetraaza-1,4,8,11-cyclotetradecane

Base Information

• Chemical Name: (<(tetrahydro-3'',4'',5'',6''-2''H-pyranyl-2)oxy>-2'-ethyl)-6-tetratosyl-1,4,8,11-tetraaza-1,4,8,11-cyclotetradecane
• CAS No.: 118467-55-3
• Molecular Formula: C₄₅H₆₀N₄O₁₀S₄
• Molecular Weight: 945.256
• Mol file: 118467-55-3.mol

Synonyms:

Chemical Property of (<(tetrahydro-3'',4'',5'',6''-2''H-pyranyl-2)oxy>-2'-ethyl)-6-tetratosyl-1,4,8,11-tetraaza-1,4,8,11-cyclotetradecane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (<(tetrahydro-3'',4'',5'',6''-2''H-pyranyl-2)oxy>-2'-ethyl)-6-tetratosyl-1,4,8,11-tetraaza-1,4,8,11-cyclotetradecane

There total 1 articles about (<(tetrahydro-3'',4'',5'',6''-2''H-pyranyl-2)oxy>-2'-ethyl)-6-tetratosyl-1,4,8,11-tetraaza-1,4,8,11-cyclotetradecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

1,4,8,11-Tetrakis(toluene-p-sulphonyl)-1,4,8,11-tetraazaundecane (111514-29-5) + 2-<2-(tetrahydropyran-2-yloxy)ethyl>propane-1,3-diol di-p-toluenesulfonate (118467-74-6) → (<(tetrahydro-3'',4'',5'',6''-2''H-pyranyl-2)oxy>-2'-ethyl)-6-tetratosyl-1,4,8,11-tetraaza-1,4,8,11-cyclotetradecane (118467-55-3)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; for 2h;

DOI:10.1002/hlca.19880710313

Reference yield:

(<(tetrahydro-3'',4'',5'',6''-2''H-pyranyl-2)oxy>-2'-ethyl)-6-tetratosyl-1,4,8,11-tetraaza-1,4,8,11-cyclotetradecane (118467-55-3) → (tetratosyl-1',4',8',11'-tetraaza-1',4',8',11'-cyclotetradecyl-6')-2-ethanol (118467-58-6)

Guidance literature:

With toluene-4-sulfonic acid; In 1,4-dioxane; for 2h; Yield given; Ambient temperature;

DOI:10.1002/hlca.19880710313

Reference yield:

(<(tetrahydro-3'',4'',5'',6''-2''H-pyranyl-2)oxy>-2'-ethyl)-6-tetratosyl-1,4,8,11-tetraaza-1,4,8,11-cyclotetradecane (118467-55-3) → (tetratosyl-1',4',8',11'-tetraaza-1',4',8',11'-cyclotetradecyl-6')-3-propiononitrile (118467-64-4)

Guidance literature:

Multi-step reaction with 3 steps

1: TsOH / dioxane / 2 h / Ambient temperature

2: 80 percent / pyridine / 3.5 h / 0 °C

3: 70 percent / dimethylsulfoxide / 2 h / 95 °C

With toluene-4-sulfonic acid; In 1,4-dioxane; pyridine; dimethyl sulfoxide;

DOI:10.1002/hlca.19880710313

upstream raw materials:

1,4,8,11-Tetrakis(toluene-p-sulphonyl)-1,4,8,11-tetraazaundecane

2-<2-(tetrahydropyran-2-yloxy)ethyl>propane-1,3-diol di-p-toluenesulfonate

Downstream raw materials:

(tetratosyl-1',4',8',11'-tetraaza-1',4',8',11'-cyclotetradecyl-6')-2-ethanol

(tetratosyl-1',4',8',11'-tetraaza-1',4',8',11'-cyclotetradecyl-6')-3-propiononitrile

(tetratosyl-1',4',8',11'-tetraaza-1',4',8',11'-cyclotetradecyl-6')-2-ethyl p-toluenesulfonate