Technology Process of 2-ethyl-3-4'-hydroxybenzoyl-3',5'-diiodo-5-nitrobenzofuran
There total 6 articles about 2-ethyl-3-4'-hydroxybenzoyl-3',5'-diiodo-5-nitrobenzofuran which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 16.6 percent / nitric acid / acetic anhydride / 3 h / Ambient temperature
2: 1.) 80 percent hydrazine hydrate; 2.) KOH / 1.) 125 deg C, 1.5 h; 2.) 140 deg C, 1 h
3: 52.7 percent / AlCl3 / CS2 / 24 h / 25 °C
4: 46.9 percent / AlCl3 / chlorobenzene / 2 h / 120 °C
5: 1.) chloroiodine; 2.) H2O / 1.) acetic acid, 25 deg C, 0.5 h; 2.) 75 deg C, 10 min
With
potassium hydroxide; aluminium trichloride; water; nitric acid; Iodine monochloride; hydrazine hydrate;
In
carbon disulfide; acetic anhydride; chlorobenzene;
DOI:10.1248/cpb.33.2854
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 52.7 percent / AlCl3 / CS2 / 24 h / 25 °C
2: 46.9 percent / AlCl3 / chlorobenzene / 2 h / 120 °C
3: 1.) chloroiodine; 2.) H2O / 1.) acetic acid, 25 deg C, 0.5 h; 2.) 75 deg C, 10 min
With
aluminium trichloride; water; Iodine monochloride;
In
carbon disulfide; chlorobenzene;
DOI:10.1248/cpb.33.2854
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) 80 percent hydrazine hydrate; 2.) KOH / 1.) 125 deg C, 1.5 h; 2.) 140 deg C, 1 h
2: 52.7 percent / AlCl3 / CS2 / 24 h / 25 °C
3: 46.9 percent / AlCl3 / chlorobenzene / 2 h / 120 °C
4: 1.) chloroiodine; 2.) H2O / 1.) acetic acid, 25 deg C, 0.5 h; 2.) 75 deg C, 10 min
With
potassium hydroxide; aluminium trichloride; water; Iodine monochloride; hydrazine hydrate;
In
carbon disulfide; chlorobenzene;
DOI:10.1248/cpb.33.2854
![1-(benzo[b]furan-2-yl)ethanone](/Databaselist/images/loading.webp)
