C₁₆H₁₅F₂NO₂

Base Information

• Chemical Name: C₁₆H₁₅F₂NO₂
• CAS No.: 1415240-31-1
• Molecular Formula: C₁₆H₁₅F₂NO₂
• Molecular Weight: 291.297
• Mol file: 1415240-31-1.mol

Synonyms:

Chemical Property of C₁₆H₁₅F₂NO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₆H₁₅F₂NO₂

There total 1 articles about C₁₆H₁₅F₂NO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

meta-hydroxybenzaldehyde (100-83-4) → C16H15F2NO2 (1415240-31-1)

Guidance literature:

Multi-step reaction with 3 steps

1: methanol; water / 0.33 h / 20 °C

2: sodium tetrahydroborate / methanol; water / 2.5 h / 0 - 20 °C

3: triethylamine / dichloromethane / 18 h / 20 °C

With sodium tetrahydroborate; triethylamine; In methanol; dichloromethane; water;

DOI:10.1016/j.bmcl.2012.09.050

Reference yield:

C16H15F2NO2 (1415240-31-1) → C16H17F2NO2 (1415240-48-0)

Guidance literature:

With sodium tetrahydroborate; In ethanol; at 0 - 20 ℃; for 1.5h;

DOI:10.1016/j.bmcl.2012.09.050

Reference yield:

C16H15F2NO2 (1415240-31-1) → C16H15F2NO (1415240-65-1)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium tetrahydroborate / ethanol / 1.5 h / 0 - 20 °C

2: sulfuric acid / dichloromethane / 0.33 h / 0 - 20 °C

With sodium tetrahydroborate; sulfuric acid; In ethanol; dichloromethane;

DOI:10.1016/j.bmcl.2012.09.050

upstream raw materials:

meta-hydroxybenzaldehyde

Downstream raw materials:

C₁₆H₁₇F₂NO₂

C₁₆H₁₅F₂NO