C₂₀H₂₄⁽²⁾H₃NO₄

Base Information

• Chemical Name: C₂₀H₂₄⁽²⁾H₃NO₄
• CAS No.: 156555-98-5
• Molecular Formula: C₂₀H₂₇NO₄
• Molecular Weight: 348.415
• Mol file: 156555-98-5.mol

Synonyms:

Chemical Property of C₂₀H₂₄⁽²⁾H₃NO₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₂₄⁽²⁾H₃NO₄

There total 5 articles about C₂₀H₂₄⁽²⁾H₃NO₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-4-Benzyl-2-oxazolidinone (90719-32-7) → C20H24(2)H3NO4 (156555-98-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 99 percent / nBuLi / tetrahydrofuran / 0 °C

2: 74 percent / NaN(SiMe₃)2, DMPU / tetrahydrofuran / -78 °C

3: 1.) Bu₂BOTf, iPr₂NEt / 1.) CH₂Cl₂, 0 deg C, 2.) CH₂Cl₂, -78 deg C

With 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; n-butyllithium; di-n-butylboryl trifluoromethanesulfonate; sodium hexamethyldisilazane; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran;

DOI:10.1016/S0040-4039(00)76541-5

Reference yield:

(S)-3-acetyl-4-benzyloxazolidin-2-one (132836-66-9) → C20H24(2)H3NO4 (156555-98-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 74 percent / NaN(SiMe₃)2, DMPU / tetrahydrofuran / -78 °C

2: 1.) Bu₂BOTf, iPr₂NEt / 1.) CH₂Cl₂, 0 deg C, 2.) CH₂Cl₂, -78 deg C

With 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; di-n-butylboryl trifluoromethanesulfonate; sodium hexamethyldisilazane; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran;

DOI:10.1016/S0040-4039(00)76541-5

Reference yield:

(S)-4-benzyl-3-((S,E)-2-methylhex-4-enoyl)oxazolidin-2-one → C20H24(2)H3NO4 (156555-98-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 70 percent / LiAlH₄ / diethyl ether / 0 °C

2: 1.) (COCl)2, DMSO, 2.) Et₃N / 1.) CH₂Cl₂, -78 deg C, 2.) CH₂Cl₂, -30 deg C

3: 1.) Bu₂BOTf, iPr₂NEt / 1.) CH₂Cl₂, 0 deg C, 2.) CH₂Cl₂, -78 deg C

With lithium aluminium tetrahydride; oxalyl dichloride; di-n-butylboryl trifluoromethanesulfonate; dimethyl sulfoxide; triethylamine; N-ethyl-N,N-diisopropylamine; In diethyl ether;

DOI:10.1016/S0040-4039(00)76541-5

upstream raw materials:

(S)-(E)-2-methyl-hex-4-enal

C₁₃H₁₂⁽²⁾H₃NO₃

(S)-4-Benzyl-2-oxazolidinone

(S)-3-acetyl-4-benzyloxazolidin-2-one