phosphoric acid 12-(2-{1-[2-(5-chloro-indol-1-yl)-ethyl]-1H-indol-3-yl}-acetylamino)-dodecyl ester 3-chloro-phenyl ester 2-cyano-ethyl ester

Base Information

• Chemical Name: phosphoric acid 12-(2-{1-[2-(5-chloro-indol-1-yl)-ethyl]-1H-indol-3-yl}-acetylamino)-dodecyl ester 3-chloro-phenyl ester 2-cyano-ethyl ester
• CAS No.: 342776-72-1
• Molecular Formula: C₄₁H₄₉Cl₂N₄O₅P
• Molecular Weight: 779.744
• Mol file: 342776-72-1.mol

Synonyms:

Chemical Property of phosphoric acid 12-(2-{1-[2-(5-chloro-indol-1-yl)-ethyl]-1H-indol-3-yl}-acetylamino)-dodecyl ester 3-chloro-phenyl ester 2-cyano-ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phosphoric acid 12-(2-{1-[2-(5-chloro-indol-1-yl)-ethyl]-1H-indol-3-yl}-acetylamino)-dodecyl ester 3-chloro-phenyl ester 2-cyano-ethyl ester

There total 5 articles about phosphoric acid 12-(2-{1-[2-(5-chloro-indol-1-yl)-ethyl]-1H-indol-3-yl}-acetylamino)-dodecyl ester 3-chloro-phenyl ester 2-cyano-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-{1-[2-(5-chloro-indol-1-yl)-ethyl]-1H-indol-3-yl}-N-(12-hydroxy-dodecyl)-acetamide (289630-00-8) → phosphoric acid 12-(2-{1-[2-(5-chloro-indol-1-yl)-ethyl]-1H-indol-3-yl}-acetylamino)-dodecyl ester 3-chloro-phenyl ester 2-cyano-ethyl ester (342776-72-1)

Guidance literature:

Multi-step reaction with 3 steps

1: iPr₂NEt / CH₂Cl₂

2: 1H-tetrazole

3: t-BuOOH

With 1H-tetrazole; tert.-butylhydroperoxide; N-ethyl-N,N-diisopropylamine; In dichloromethane;

DOI:10.1016/S0960-894X(01)00002-6

Reference yield:

12-(2-{1-[2-(5-chloro-indol-1-yl)-ethyl]-1H-indol-3-yl}-acetylamino)-dodecanoic acid methyl ester → phosphoric acid 12-(2-{1-[2-(5-chloro-indol-1-yl)-ethyl]-1H-indol-3-yl}-acetylamino)-dodecyl ester 3-chloro-phenyl ester 2-cyano-ethyl ester (342776-72-1)

Guidance literature:

Multi-step reaction with 4 steps

1: LiAlH₄ / tetrahydrofuran

2: iPr₂NEt / CH₂Cl₂

3: 1H-tetrazole

4: t-BuOOH

With 1H-tetrazole; tert.-butylhydroperoxide; lithium aluminium tetrahydride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane;

DOI:10.1016/S0960-894X(01)00002-6

Reference yield:

phosphorous acid 12-(2-{1-[2-(5-chloro-indol-1-yl)-ethyl]-1H-indol-3-yl}-acetylamino)-dodecyl ester 3-chloro-phenyl ester 2-cyano-ethyl ester → phosphoric acid 12-(2-{1-[2-(5-chloro-indol-1-yl)-ethyl]-1H-indol-3-yl}-acetylamino)-dodecyl ester 3-chloro-phenyl ester 2-cyano-ethyl ester (342776-72-1)

Guidance literature:

With tert.-butylhydroperoxide;

DOI:10.1016/S0960-894X(01)00002-6

upstream raw materials:

3-monochlorophenol

2-{1-[2-(5-chloro-indol-1-yl)-ethyl]-1H-indol-3-yl}-N-(12-hydroxy-dodecyl)-acetamide