Technology Process of C12H20O
There total 4 articles about C12H20O which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(1α,2β,Z)-2-(Hex-1-enyl)cyclohexanol;
With
oxalyl dichloride; dimethyl sulfoxide;
In
dichloromethane;
at -78 ℃;
for 0.333333h;
Inert atmosphere;
With
N-ethyl-N,N-diisopropylamine;
In
dichloromethane;
at -78 - 0 ℃;
for 0.666667h;
Inert atmosphere;
DOI:10.1021/ja109165f
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: rac-Pro-OH / dichloromethane / 13.5 h / 20 °C / Inert atmosphere
2.1: sodium hexamethyldisilazane / tetrahydrofuran / 1.33 h / 0 °C / Inert atmosphere
2.2: 1 h / 0 °C / Inert atmosphere
3.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.33 h / -78 °C / Inert atmosphere
3.2: 0.67 h / -78 - 0 °C / Inert atmosphere
With
oxalyl dichloride; sodium hexamethyldisilazane; dimethyl sulfoxide; rac-Pro-OH;
In
tetrahydrofuran; dichloromethane;
1.1: Aldol condensation / 2.2: Wittig reaction;
DOI:10.1021/ja109165f
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hexamethyldisilazane / tetrahydrofuran / 1.33 h / 0 °C / Inert atmosphere
1.2: 1 h / 0 °C / Inert atmosphere
2.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.33 h / -78 °C / Inert atmosphere
2.2: 0.67 h / -78 - 0 °C / Inert atmosphere
With
oxalyl dichloride; sodium hexamethyldisilazane; dimethyl sulfoxide;
In
tetrahydrofuran; dichloromethane;
1.2: Wittig reaction;
DOI:10.1021/ja109165f
