C₂₀H₂₀N₂O₅S

Base Information

• Chemical Name: C₂₀H₂₀N₂O₅S
• CAS No.: 1448788-51-9
• Molecular Formula: C₂₀H₂₀N₂O₅S
• Molecular Weight: 400.455
• Mol file: 1448788-51-9.mol

Synonyms:

Chemical Property of C₂₀H₂₀N₂O₅S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₂₀N₂O₅S

There total 7 articles about C₂₀H₂₀N₂O₅S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl(3-isopropoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)dimethylsilane (1352571-02-8) → C20H20N2O5S (1448788-51-9)

Guidance literature:

Multi-step reaction with 4 steps

1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / 1,2-dimethoxyethane; water / 13 h / 70 °C

2: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 23 °C

3: potassium carbonate / N,N-dimethyl-formamide / 13 h / 120 °C

4: trifluoroacetic acid / 0.5 h / 23 °C

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; tetrabutyl ammonium fluoride; sodium carbonate; potassium carbonate; trifluoroacetic acid; In tetrahydrofuran; 1,2-dimethoxyethane; water; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2013.06.036

Reference yield:

3-isopropoxyphenol (68792-12-1) → C20H20N2O5S (1448788-51-9)

Guidance literature:

Multi-step reaction with 6 steps

1: 1H-imidazole / dichloromethane / 1 h / 23 °C

2: 4,4'-di-tert-butyl-2,2'-bipyridine; (1,5-cyclooctadiene)(methoxy)iridium(I) dimer / tert-butyl methyl ether / 10 h / 100 °C / Microwave irradiation

3: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / 1,2-dimethoxyethane; water / 13 h / 70 °C

4: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 23 °C

5: potassium carbonate / N,N-dimethyl-formamide / 13 h / 120 °C

6: trifluoroacetic acid / 0.5 h / 23 °C

With 1H-imidazole; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; tetrabutyl ammonium fluoride; sodium carbonate; potassium carbonate; trifluoroacetic acid; 4,4'-di-tert-butyl-2,2'-bipyridine; In tetrahydrofuran; 1,2-dimethoxyethane; dichloromethane; tert-butyl methyl ether; water; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2013.06.036

Reference yield:

C27H36N2O4Si → C20H20N2O5S (1448788-51-9)

Guidance literature:

Multi-step reaction with 3 steps

1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 23 °C

2: potassium carbonate / N,N-dimethyl-formamide / 13 h / 120 °C

3: trifluoroacetic acid / 0.5 h / 23 °C

With tetrabutyl ammonium fluoride; potassium carbonate; trifluoroacetic acid; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2013.06.036

upstream raw materials:

recorcinol

3-isopropoxyphenol

tert-butyl(3-isopropoxyphenoxy)dimethylsilane

tert-butyl(3-isopropoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)dimethylsilane

Refernces