Technology Process of C13H19N3O2
There total 5 articles about C13H19N3O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: lithium hexamethyldisilazane / tetrahydrofuran; ethyl acetate / -78 °C
1.2: 20 °C
2.1: diphenyl phosphoryl azide; triethylamine / toluene / 8.5 h / 20 °C / Reflux
3.1: palladium on activated charcoal; hydrogen / methanol / 4 h / 2585.81 Torr
4.1: triethylamine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate / dichloromethane
5.1: lithium hydroxide monohydrate / water; 1,4-dioxane / 5 h / 70 °C
With
lithium hydroxide monohydrate; diphenyl phosphoryl azide; palladium on activated charcoal; hydrogen; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; lithium hexamethyldisilazane;
In
tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; water; ethyl acetate; toluene;
DOI:10.1016/j.bmcl.2012.12.078
- Guidance literature:
-
Multi-step reaction with 4 steps
1: diphenyl phosphoryl azide; triethylamine / toluene / 8.5 h / 20 °C / Reflux
2: palladium on activated charcoal; hydrogen / methanol / 4 h / 2585.81 Torr
3: triethylamine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate / dichloromethane
4: lithium hydroxide monohydrate / water; 1,4-dioxane / 5 h / 70 °C
With
lithium hydroxide monohydrate; diphenyl phosphoryl azide; palladium on activated charcoal; hydrogen; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine;
In
1,4-dioxane; methanol; dichloromethane; water; toluene;
DOI:10.1016/j.bmcl.2012.12.078
