C₁₀H₁₁NO

Base Information

• Chemical Name: C₁₀H₁₁NO
• CAS No.: 1380392-38-0
• Molecular Formula: C₁₀H₁₁NO
• Molecular Weight: 161.203
• Mol file: 1380392-38-0.mol

Synonyms:

Chemical Property of C₁₀H₁₁NO

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of C₁₀H₁₁NO

There total 1 articles about C₁₀H₁₁NO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

crotylmagnesium chloride (21969-32-4) + nitrobenzene (98-95-3,26969-40-4) → (E)-N-(but-3-en-2-ylidene)aniline oxide (1380392-38-0,848190-18-1)

Guidance literature:

In tetrahydrofuran; at -78 ℃; for 0.25h; Inert atmosphere;

DOI:10.1002/anie.201200860

Reference yield:

C10H11NO (1380392-38-0,848190-18-1) → 4-(1H-indol-3-yl)-2-butanone (5541-89-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: toluene / 14 h / 80 °C

2.1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; (R,R)-ANDEN-phenyl Trost ligand / tetrahydrofuran / 0.03 h / 0 °C / Inert atmosphere

2.2: 16 h / 23 °C / Inert atmosphere

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; (R,R)-ANDEN-phenyl Trost ligand; In tetrahydrofuran; toluene;

DOI:10.1002/ejoc.201300515

upstream raw materials:

crotylmagnesium chloride

nitrobenzene

Downstream raw materials:

4-(1H-indol-3-yl)-2-butanone