9-(2-deoxy-5-O-phosphonopentofuranosyl)-N-[(1S,2S,3R,4S)-2,3,4-trihydroxy-7-methyl-1,2,3,4-tetrahydrotetraphen-1-yl]-9H-purin-6-amine

Base Information Edit

Chemical Name:9-(2-deoxy-5-O-phosphonopentofuranosyl)-N-[(1S,2S,3R,4S)-2,3,4-trihydroxy-7-methyl-1,2,3,4-tetrahydrotetraphen-1-yl]-9H-purin-6-amine
CAS No.:133645-05-3
Molecular Formula:C₂₉H₂₉N₅O₆
Molecular Weight:543.579
Hs Code.:
Mol file:133645-05-3.mol

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 9-(2-deoxy-5-O-phosphonopentofuranosyl)-N-[(1S,2S,3R,4S)-2,3,4-trihydroxy-7-methyl-1,2,3,4-tetrahydrotetraphen-1-yl]-9H-purin-6-amine Edit

Chemical Property:

Vapor Pressure:0mmHg at 25°C

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Technology Process of 9-(2-deoxy-5-O-phosphonopentofuranosyl)-N-[(1S,2S,3R,4S)-2,3,4-trihydroxy-7-methyl-1,2,3,4-tetrahydrotetraphen-1-yl]-9H-purin-6-amine

There total 4 articles about 9-(2-deoxy-5-O-phosphonopentofuranosyl)-N-[(1S,2S,3R,4S)-2,3,4-trihydroxy-7-methyl-1,2,3,4-tetrahydrotetraphen-1-yl]-9H-purin-6-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 133645-02-0,63057-64-7,64625-66-7
(+/-)-trans-3,4-Dihydroxy-anti-1,2-epoxy-7-methyl-1,2,3,4-tetrahydrobenz anthracene

: 653-63-4
2'-deoxyadenosine-5'-monophosphoric acid

: 133551-47-0,133645-04-2,133645-05-3,133645-06-4
Phosphoric acid mono-{(2R,3S,5R)-3-hydroxy-5-[6-(2,3,4-trihydroxy-7-methyl-1,2,3,4-tetrahydro-benzo[a]anthracen-1-ylamino)-purin-9-yl]-tetrahydro-furan-2-ylmethyl} ester

Guidance literature:: With tris-HCl-buffer; In acetone; at 37 ℃;
DOI:10.1021/jo00013a020

Reference yield:

: 133645-02-0,63057-64-7,64625-66-7
(+/-)-trans-3,4-Dihydroxy-anti-1,2-epoxy-7-methyl-1,2,3,4-tetrahydrobenz anthracene

: 133645-05-3
(1S,2S,3R,4S)-1-[9-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-ylamino]-7-methyl-1,2,3,4-tetrahydro-benzo[a]anthracene-2,3,4-triol

: 133551-47-0
(1S,2R,3S,4R)-1-[9-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-ylamino]-7-methyl-1,2,3,4-tetrahydro-benzo[a]anthracene-2,3,4-triol

: 133645-04-2
(1R,2S,3R,4S)-1-[9-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-ylamino]-7-methyl-1,2,3,4-tetrahydro-benzo[a]anthracene-2,3,4-triol

Guidance literature:: With tris-HCl-buffer; Multistep reaction; 1.) acetone, 37 deg C, 2.) snake venom phosphodiesterase, alkal. phosphomonoesterase;
DOI:10.1021/jo00013a020