(S)-3-(4-Benzyloxy-phenyl)-2-{(S)-2-[(S)-2-((S)-2-tert-butoxycarbonylamino-4-methyl-pentanoylamino)-4-methyl-pentanoylamino]-3-methyl-butyrylamino}-propionic acid benzyl ester

Base Information

• Chemical Name: (S)-3-(4-Benzyloxy-phenyl)-2-{(S)-2-[(S)-2-((S)-2-tert-butoxycarbonylamino-4-methyl-pentanoylamino)-4-methyl-pentanoylamino]-3-methyl-butyrylamino}-propionic acid benzyl ester
• CAS No.: 52799-90-3
• Molecular Formula: C₄₅H₆₂N₄O₈
• Molecular Weight: 787.009

Synonyms:

Chemical Property of (S)-3-(4-Benzyloxy-phenyl)-2-{(S)-2-[(S)-2-((S)-2-tert-butoxycarbonylamino-4-methyl-pentanoylamino)-4-methyl-pentanoylamino]-3-methyl-butyrylamino}-propionic acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-3-(4-Benzyloxy-phenyl)-2-{(S)-2-[(S)-2-((S)-2-tert-butoxycarbonylamino-4-methyl-pentanoylamino)-4-methyl-pentanoylamino]-3-methyl-butyrylamino}-propionic acid benzyl ester

There total 7 articles about (S)-3-(4-Benzyloxy-phenyl)-2-{(S)-2-[(S)-2-((S)-2-tert-butoxycarbonylamino-4-methyl-pentanoylamino)-4-methyl-pentanoylamino]-3-methyl-butyrylamino}-propionic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-3-(4-Benzyloxy-phenyl)-2-[(S)-2-((S)-2-tert-butoxycarbonylamino-4-methyl-pentanoylamino)-3-methyl-butyrylamino]-propionic acid benzyl ester (52799-87-8) → (S)-3-(4-Benzyloxy-phenyl)-2-{(S)-2-[(S)-2-((S)-2-tert-butoxycarbonylamino-4-methyl-pentanoylamino)-4-methyl-pentanoylamino]-3-methyl-butyrylamino}-propionic acid benzyl ester (52799-90-3)

Guidance literature:

Multi-step reaction with 2 steps

1: trifluoroacetic acid / 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran

2: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine / 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; trifluoroacetic acid; In 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran;

DOI:10.1002/ejoc.201801490

Reference yield:

3-(4-benzyloxyphenyl)-L-alanine benzyl ester p-toluenesulfonate → (S)-3-(4-Benzyloxy-phenyl)-2-{(S)-2-[(S)-2-((S)-2-tert-butoxycarbonylamino-4-methyl-pentanoylamino)-4-methyl-pentanoylamino]-3-methyl-butyrylamino}-propionic acid benzyl ester (52799-90-3)

Guidance literature:

Multi-step reaction with 5 steps

1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine / 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran

2: trifluoroacetic acid / 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran

3: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine / 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran

4: trifluoroacetic acid / 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran

5: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine / 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; trifluoroacetic acid; In 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran;

DOI:10.1002/ejoc.201801490

Reference yield:

t-Boc-L-valine (13734-41-3) → (S)-3-(4-Benzyloxy-phenyl)-2-{(S)-2-[(S)-2-((S)-2-tert-butoxycarbonylamino-4-methyl-pentanoylamino)-4-methyl-pentanoylamino]-3-methyl-butyrylamino}-propionic acid benzyl ester (52799-90-3)

Guidance literature:

Multi-step reaction with 5 steps

1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine / 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran

2: trifluoroacetic acid / 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran

3: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine / 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran

4: trifluoroacetic acid / 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran

5: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine / 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; trifluoroacetic acid; In 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran;

DOI:10.1002/ejoc.201801490

upstream raw materials:

t-Boc-L-valine

Boc-Val-Tyr(-CH₂C₆H₅)-OCH₂C₆H₅

(S)-3-(4-Benzyloxy-phenyl)-2-[(S)-2-((S)-2-tert-butoxycarbonylamino-4-methyl-pentanoylamino)-3-methyl-butyrylamino]-propionic acid benzyl ester

N-tert-butoxycarbonyl-L-leucine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 52799-90-3 (S)-3-(4-Benzyloxy-phenyl)-2-{(S)-2-[(S)-2-((S)-2-tert-butoxycarbonylamino-4-methyl-pentanoylamino)-4-methyl-pentanoylamino]-3-methyl-butyrylamino}-propionic acid benzyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send