Phenyl-o-tolyl-acetylchlorid

Base Information

• Chemical Name: Phenyl-o-tolyl-acetylchlorid
• CAS No.: 92435-45-5
• Molecular Formula: C₁₅H₁₃ClO
• Molecular Weight: 244.721
• Mol file: 92435-45-5.mol

Synonyms:

Chemical Property of Phenyl-o-tolyl-acetylchlorid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Phenyl-o-tolyl-acetylchlorid

There total 6 articles about Phenyl-o-tolyl-acetylchlorid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ortho-tolylmagnesium bromide (932-31-0) → Phenyl-o-tolyl-acetylchlorid (92435-45-5)

Guidance literature:

Multi-step reaction with 5 steps

1: 66 percent / diethyl ether

2: SOCl₂

3: 73 percent / ethanol; H₂O

4: concd. HCl

5: SOCl₂

With hydrogenchloride; thionyl chloride; In diethyl ether; ethanol; water;

DOI:10.1021/jo00350a014

Reference yield:

α-phenyl-o-methylbenzyl chloride (41870-52-4) → Phenyl-o-tolyl-acetylchlorid (92435-45-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 73 percent / ethanol; H₂O

2: concd. HCl

3: SOCl₂

With hydrogenchloride; thionyl chloride; In ethanol; water;

DOI:10.1021/jo00350a014

Reference yield:

2-methylbenzhydrol (5472-13-9) → Phenyl-o-tolyl-acetylchlorid (92435-45-5)

Guidance literature:

Multi-step reaction with 4 steps

1: SOCl₂

2: 73 percent / ethanol; H₂O

3: concd. HCl

4: SOCl₂

With hydrogenchloride; thionyl chloride; In ethanol; water;

DOI:10.1021/jo00350a014

upstream raw materials:

2-phenyl-2-(o-tolyl)acetic acid

ortho-tolylmagnesium bromide

α-phenyl-o-methylbenzyl chloride

2-methylbenzhydrol

Downstream raw materials:

N-tert-butyl-2-phenyl-2-o-tolylacetamide

Refernces