Potassium; (6R,7R)-7-{2-[(Z)-methoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-8-oxo-3-p-tolylsulfanylmethyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate

Base Information

Chemical Name:Potassium; (6R,7R)-7-{2-[(Z)-methoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-8-oxo-3-p-tolylsulfanylmethyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate
CAS No.:139080-51-6
Molecular Formula:C₄₀H₃₄N₅O₅S₃*K
Molecular Weight:800.037
Hs Code.:

Potassium; (6R,7R)-7-{2-[(Z)-methoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-8-oxo-3-p-tolylsulfanylmethyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate

Synonyms:

Suppliers and Price of Potassium; (6R,7R)-7-{2-[(Z)-methoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-8-oxo-3-p-tolylsulfanylmethyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Potassium; (6R,7R)-7-{2-[(Z)-methoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-8-oxo-3-p-tolylsulfanylmethyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Potassium; (6R,7R)-7-{2-[(Z)-methoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-8-oxo-3-p-tolylsulfanylmethyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate

There total 5 articles about Potassium; (6R,7R)-7-{2-[(Z)-methoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-8-oxo-3-p-tolylsulfanylmethyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 139112-05-3
(6R,7R)-7-{2-[(Z)-Methoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-8-oxo-3-p-tolylsulfanylmethyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

: 139080-51-6
Potassium; (6R,7R)-7-{2-[(Z)-methoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-8-oxo-3-p-tolylsulfanylmethyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate

Guidance literature:: With potassium 2-ethylhexanoate; methoxybenzene; trifluoroacetic acid; at 0 - 5 ℃; for 2h;

Reference yield:

: 76609-91-1
2-(2-tritylamino-4-thiazolyl)-2-methoxyiminoacetyl chloride

: 139080-51-6
Potassium; (6R,7R)-7-{2-[(Z)-methoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-8-oxo-3-p-tolylsulfanylmethyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: aq. NaHCO₃, Et₃N / acetone / 1.5 h

2: 60 percent / CH₂Cl₂; methanol / 2 h / Ambient temperature

3: 63 percent / 1.) trifluoroacetic acid, anisole, 2.) potassium 2-ethyl hexanoate / 2 h / 0 - 5 °C

With sodium hydrogencarbonate; potassium 2-ethylhexanoate; methoxybenzene; triethylamine; trifluoroacetic acid; In methanol; dichloromethane; acetone;

Reference yield:

: (6R,7R)-7-Amino-8-oxo-3-p-tolylsulfanylmethyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid

: 139080-51-6
Potassium; (6R,7R)-7-{2-[(Z)-methoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-8-oxo-3-p-tolylsulfanylmethyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: aq. NaHCO₃, Et₃N / acetone / 1.5 h

2: 60 percent / CH₂Cl₂; methanol / 2 h / Ambient temperature

3: 63 percent / 1.) trifluoroacetic acid, anisole, 2.) potassium 2-ethyl hexanoate / 2 h / 0 - 5 °C

With sodium hydrogencarbonate; potassium 2-ethylhexanoate; methoxybenzene; triethylamine; trifluoroacetic acid; In methanol; dichloromethane; acetone;