6-Fluoro-4-cinnolinol

Base Information

Chemical Name:6-Fluoro-4-cinnolinol
CAS No.:876-90-4
Molecular Formula:C₈H₅FN₂O
Molecular Weight:164.139
Hs Code.:
NSC Number:66069
UNII:266ZH5EWY7
DSSTox Substance ID:DTXSID10236515
Wikidata:Q83118486

Synonyms:6-Fluoro-4-cinnolinol;876-90-4;6-fluorocinnolin-4-ol;6-Fluoro-4-hydroxycinnoline;6-fluoro-1H-cinnolin-4-one;266ZH5EWY7;NSC66069;NSC 66069;UNII-266ZH5EWY7;NSC-66069;4-Cinnolinol, 6-fluoro-;6-Fluorocinnolin-4(1H)-one;SCHEMBL2719952;DTXSID10236515;AC7050;MFCD29071920;6-fluoro-1,4-dihydrocinnolin-4-one;SY235839;EN300-345264;A915497

Suppliers and Price of 6-Fluoro-4-cinnolinol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 6-Fluoro-4-cinnolinol

Chemical Property:

Vapor Pressure:0.000365mmHg at 25°C
Boiling Point:318.3°C at 760 mmHg
Flash Point:146.3°C
Density:1.44g/cm³
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:164.03859095
Heavy Atom Count:12
Complexity:229

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C1F)C(=O)C=NN2

Technology Process of 6-Fluoro-4-cinnolinol

There total 3 articles about 6-Fluoro-4-cinnolinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 887903-01-7
4-fluoro-2-trimethylsilanylethynylphenylamine

: 876-90-4
6-fluoro-1H-cinnolin-4-one

Guidance literature:: 4-fluoro-2-trimethylsilanylethynylphenylamine; With hydrogenchloride; sodium nitrite; In water; at 100 ℃; for 3.5h;

With sodium hydrogencarbonate; In water; at 20 ℃;

Reference yield:

: 1003-98-1
2-bromo-4-fluoroaniline

: 876-90-4
6-fluoro-1H-cinnolin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine / copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride / N,N-dimethyl-formamide / 4 h / 50 °C / Inert atmosphere

2.1: hydrogenchloride; sodium nitrite / water / 3.5 h / 100 °C

2.2: 20 °C

With hydrogenchloride; triethylamine; sodium nitrite; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In water; N,N-dimethyl-formamide;