3-chloro-4-ethoxyaniline hydrochloride

Base Information

• Chemical Name: 3-chloro-4-ethoxyaniline hydrochloride
• CAS No.: 1185108-72-8
• Molecular Formula: C₈H₁₀ClNO*(x)ClH
• Molecular Weight: 208.08504
• Mol file: 1185108-72-8.mol

Synonyms:

Chemical Property of 3-chloro-4-ethoxyaniline hydrochloride

Chemical Property:

Purity/Quality:

98%min ^*data from raw suppliers

3-Chloro-4-ethoxyanilineHydrochloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

Useful:

Technology Process of 3-chloro-4-ethoxyaniline hydrochloride

There total 2 articles about 3-chloro-4-ethoxyaniline hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.4%

N-(4-ethoxyphenyl)-α-phenylnitrone → 3-chloro-4-ethoxyaniline hydrochloride (1185108-72-8)

Guidance literature:

N-(4-ethoxyphenyl)-α-phenylnitrone; With oxalyl dichloride; In tetrahydrofuran; at 0 - 25 ℃; for 2.5h; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; water; at 72 ℃; for 4h;

Reference yield:

N-hydroxyphenetidine (38246-95-6) → 3-chloro-4-phenetidine hydrochloride (1185108-72-8)

Guidance literature:

With hydrogenchloride; Ambient temperature;

DOI:10.1021/jo00252a003

upstream raw materials:

N-hydroxyphenetidine