(+/-)-4c-phthalimidocyclohex-2-enyl trichloroacetimidate

Base Information

• Chemical Name: (+/-)-4c-phthalimidocyclohex-2-enyl trichloroacetimidate
• CAS No.: 131244-22-9
• Molecular Formula: C₁₆H₁₃Cl₃N₂O₃
• Molecular Weight: 387.65
• Mol file: 131244-22-9.mol

Synonyms:

Chemical Property of (+/-)-4c-phthalimidocyclohex-2-enyl trichloroacetimidate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-4c-phthalimidocyclohex-2-enyl trichloroacetimidate

There total 3 articles about (+/-)-4c-phthalimidocyclohex-2-enyl trichloroacetimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-ethoxycarbonylphthalimide (22509-74-6) → (+/-)-4c-phthalimidocyclohex-2-enyl trichloroacetimidate (131244-22-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / Na₂CO₃ / acetone / 5 h / Heating

2: 1) NaH / 1) methylene dichloride, 0 deg C, 2) 0 deg C, 1 h

With sodium hydride; sodium carbonate; In acetone;

DOI:10.1039/P19900002255

Reference yield:

(1S*,4R*)-4-aminocyclohex-2-enol (77803-77-1,96093-87-7,131321-46-5) → (+/-)-4c-phthalimidocyclohex-2-enyl trichloroacetimidate (131244-22-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / Na₂CO₃ / acetone / 5 h / Heating

2: 1) NaH / 1) methylene dichloride, 0 deg C, 2) 0 deg C, 1 h

With sodium hydride; sodium carbonate; In acetone;

DOI:10.1039/P19900002255

Reference yield:

(+/-)-4c-phthalimidocyclohex-2-en-1r-ol (131244-18-3) + trichloroacetonitrile (545-06-2) → (+/-)-4c-phthalimidocyclohex-2-enyl trichloroacetimidate (131244-22-9)

Guidance literature:

With sodium hydride; Yield given. Multistep reaction; 1) methylene dichloride, 0 deg C, 2) 0 deg C, 1 h;

DOI:10.1039/P19900002255

upstream raw materials:

(+/-)-4c-phthalimidocyclohex-2-en-1r-ol

trichloroacetonitrile

N-ethoxycarbonylphthalimide

(1S*,4R*)-4-aminocyclohex-2-enol

Downstream raw materials:

(+/-)-2c,4c-diaminocyclohexan-1r-ol

(+/-)-3t-iodo-4c-phthalimido-2c-trichloracetamidocyclohexyl acetate

(+/-)-2c-acetamido-4c-phthalimidocyclohexyl acetate