1-(1-Methylethyl)-3-phenyl-3-piperidinol

Base Information

Chemical Name:1-(1-Methylethyl)-3-phenyl-3-piperidinol
CAS No.:77799-74-7
Molecular Formula:C₁₄H₂₁NO
Molecular Weight:219.327
Hs Code.:
DSSTox Substance ID:DTXSID201274393

Synonyms:1-(1-Methylethyl)-3-phenyl-3-piperidinol;SCHEMBL10642751;DTXSID201274393;77799-74-7

Suppliers and Price of 1-(1-Methylethyl)-3-phenyl-3-piperidinol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(1-Methylethyl)-3-phenyl-3-piperidinol

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:219.162314293
Heavy Atom Count:16
Complexity:223

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)N1CCCC(C1)(C2=CC=CC=C2)O

Technology Process of 1-(1-Methylethyl)-3-phenyl-3-piperidinol

There total 3 articles about 1-(1-Methylethyl)-3-phenyl-3-piperidinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: phenylmagnesium bromide

: 77799-73-6
1-isopropylpiperidin-3-one

: 77799-74-7
1-isopropyl-3-phenyl-3-piperidinol

Guidance literature:: In diethyl ether; Ambient temperature;

Reference yield:

: 6859-99-0
3-hydroxypiperazine

: 77799-74-7
1-isopropyl-3-phenyl-3-piperidinol

Guidance literature:: Multi-step reaction with 3 steps

1: 73 percent / potassium hydroxide / ethanol / 48 h / Heating

2: 53 percent / chromic trioxide, H₂SO₄ / acetone; acetic acid; H₂O / 5 h / 0 °C

3: 54 percent / diethyl ether / Ambient temperature

With chromium(VI) oxide; potassium hydroxide; sulfuric acid; In diethyl ether; ethanol; water; acetic acid; acetone;

Reference yield:

: 3554-62-9
1-isopropyl-3-hydroxypiperidine

: 77799-74-7
1-isopropyl-3-phenyl-3-piperidinol

Guidance literature:: Multi-step reaction with 2 steps

1: 53 percent / chromic trioxide, H₂SO₄ / acetone; acetic acid; H₂O / 5 h / 0 °C

2: 54 percent / diethyl ether / Ambient temperature

With chromium(VI) oxide; sulfuric acid; In diethyl ether; water; acetic acid; acetone;