1-Formyl-5-methyl-3-phenyl-2-benzimidazolinon

Base Information

• Chemical Name: 1-Formyl-5-methyl-3-phenyl-2-benzimidazolinon
• CAS No.: 78162-54-6
• Molecular Formula: C₁₅H₁₂N₂O₂
• Molecular Weight: 252.272
• Mol file: 78162-54-6.mol

Synonyms:

Chemical Property of 1-Formyl-5-methyl-3-phenyl-2-benzimidazolinon

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Formyl-5-methyl-3-phenyl-2-benzimidazolinon

There total 3 articles about 1-Formyl-5-methyl-3-phenyl-2-benzimidazolinon which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

N-(4-Tolyl)formohydroxamsaeure (73747-07-6) + phenylcarbonimidic dichloride (622-44-6) → 1-Formyl-5-methyl-3-phenyl-2-benzimidazolinon (78162-54-6)

Guidance literature:

With TEA; In tetrahydrofuran; 1.) ice-cooling, 3 h, 2.) room temp., 12 h;

DOI:10.1002/ardp.19813140402

Reference yield: 25.0%

1-(N-Cyclohexylformimidoyl)-5-methyl-3-phenyl-2-benzimidazolinon (345320-48-1) → 6-Methyl-1-phenyl-2-benzimidazolinon (78162-53-5) + 1-Formyl-5-methyl-3-phenyl-2-benzimidazolinon (78162-54-6)

Guidance literature:

With hydrogenchloride; In ethanol;

DOI:10.1002/ardp.19813140402

Reference yield:

phenylcarbonimidic dichloride (622-44-6) → 1-Formyl-5-methyl-3-phenyl-2-benzimidazolinon (78162-54-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 47 percent / TEA / CH₂Cl₂ / 1.) ice-cooling, 3 h, 2.) room temp., 12 h

2: 25 percent / conc. aq. HCl / ethanol

With hydrogenchloride; TEA; In ethanol; dichloromethane;

DOI:10.1002/ardp.19813140402

upstream raw materials:

N-(4-Tolyl)formohydroxamsaeure

phenylcarbonimidic dichloride

1-(N-Cyclohexylformimidoyl)-5-methyl-3-phenyl-2-benzimidazolinon

Refernces