Technology Process of benzyl O-(2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-(1->4)-2-acetamido-2-deoxy-6-O-(p-methoxyphenyl)-β-D-allopyranoside
There total 6 articles about benzyl O-(2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-(1->4)-2-acetamido-2-deoxy-6-O-(p-methoxyphenyl)-β-D-allopyranoside which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 90 percent / triphenylphosphine, diisopropyl azodicarboxylate / tetrahydrofuran / 1 h / 70 °C
2: 63 percent / molecular sieves 4A, trimethylsilyl triflate / CH2Cl2 / Ambient temperature
3: 1.) 2)2>PF6, hydrogen, 2.) I2 / 1.) THF, room temperature, 2 h, 2.) THF, water, room temperature, 3 h
With
(1,5-cyclooctadiene)bis(methyldiphenylphosphine) iridium hexafluorophosphate; trimethylsilyl trifluoromethanesulfonate; di-isopropyl azodicarboxylate; 4 A molecular sieve; hydrogen; iodine; triphenylphosphine;
In
tetrahydrofuran; dichloromethane;
DOI:10.1021/jo971784a
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) NaH / 1.) DMF, 5 min, 2.) DMF, room temperature, 1 h
2: 91 percent / camphorsulfonic acid / methanol / 1 h / 60 °C
3: 90 percent / triphenylphosphine, diisopropyl azodicarboxylate / tetrahydrofuran / 1 h / 70 °C
4: 63 percent / molecular sieves 4A, trimethylsilyl triflate / CH2Cl2 / Ambient temperature
5: 1.) 2)2>PF6, hydrogen, 2.) I2 / 1.) THF, room temperature, 2 h, 2.) THF, water, room temperature, 3 h
With
(1,5-cyclooctadiene)bis(methyldiphenylphosphine) iridium hexafluorophosphate; trimethylsilyl trifluoromethanesulfonate; di-isopropyl azodicarboxylate; 4 A molecular sieve; camphor-10-sulfonic acid; hydrogen; iodine; sodium hydride; triphenylphosphine;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jo971784a
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 90 percent / triphenylphosphine, diisopropyl azodicarboxylate / tetrahydrofuran / 1 h / 70 °C
2: 63 percent / molecular sieves 4A, trimethylsilyl triflate / CH2Cl2 / Ambient temperature
3: 1.) 2)2>PF6, hydrogen, 2.) I2 / 1.) THF, room temperature, 2 h, 2.) THF, water, room temperature, 3 h
With
(1,5-cyclooctadiene)bis(methyldiphenylphosphine) iridium hexafluorophosphate; trimethylsilyl trifluoromethanesulfonate; di-isopropyl azodicarboxylate; 4 A molecular sieve; hydrogen; iodine; triphenylphosphine;
In
tetrahydrofuran; dichloromethane;
DOI:10.1021/jo971784a
