Technology Process of 3,6-anhydro-2,7-dideoxy-2-(2,2-diphenylhydrazino)-L-glycero-D-gulo-heptono-1,4-lactone
There total 9 articles about 3,6-anhydro-2,7-dideoxy-2-(2,2-diphenylhydrazino)-L-glycero-D-gulo-heptono-1,4-lactone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
2,2'-azobis(isobutyronitrile); triphenylstannane;
In
toluene;
for 2h;
Heating;
DOI:10.1021/jo982205k
- Guidance literature:
-
Multi-step reaction with 9 steps
1: HCl / 5 - 10 °C
2: pyridine / 24 h
3: 1.) acetic acid, acetic anhydride, H2SO4, 2.) BF3*OEt2 / 1.) room temperature, overnight, 2.) CH2Cl2, 0 deg C, 36 h
4: 99 percent / K2CO3 / tetrahydrofuran; methanol / 0.33 h
5: 89 percent / p-toluenesulfonic acid monohydrate / 1.5 h
6: 95 percent / 1,3-dicyclohexylcarbodiimide, 4-(dimethylamino)pyridine / CH2Cl2 / 12 h
7: 96 percent / camphorsulfonic acid / methanol / 3.5 h
8: 75 percent / tributylphosphine / tetrahydrofuran / 1.5 h
9: 37 percent / Ph3SnH, azobis(isobutyronitrile) / toluene / 2 h / Heating
With
pyridine; hydrogenchloride; dmap; 2,2'-azobis(isobutyronitrile); tributylphosphine; sulfuric acid; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; triphenylstannane; acetic anhydride; potassium carbonate; toluene-4-sulfonic acid; acetic acid; dicyclohexyl-carbodiimide;
In
tetrahydrofuran; methanol; dichloromethane; toluene;
DOI:10.1021/jo982205k
- Guidance literature:
-
Multi-step reaction with 8 steps
1: pyridine / 24 h
2: 1.) acetic acid, acetic anhydride, H2SO4, 2.) BF3*OEt2 / 1.) room temperature, overnight, 2.) CH2Cl2, 0 deg C, 36 h
3: 99 percent / K2CO3 / tetrahydrofuran; methanol / 0.33 h
4: 89 percent / p-toluenesulfonic acid monohydrate / 1.5 h
5: 95 percent / 1,3-dicyclohexylcarbodiimide, 4-(dimethylamino)pyridine / CH2Cl2 / 12 h
6: 96 percent / camphorsulfonic acid / methanol / 3.5 h
7: 75 percent / tributylphosphine / tetrahydrofuran / 1.5 h
8: 37 percent / Ph3SnH, azobis(isobutyronitrile) / toluene / 2 h / Heating
With
pyridine; dmap; 2,2'-azobis(isobutyronitrile); tributylphosphine; sulfuric acid; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; triphenylstannane; acetic anhydride; potassium carbonate; toluene-4-sulfonic acid; acetic acid; dicyclohexyl-carbodiimide;
In
tetrahydrofuran; methanol; dichloromethane; toluene;
DOI:10.1021/jo982205k
