Technology Process of dimethyl (2R,3R,4S)-2,4-diacetoxy-3-benzyloxy-1,1-cyclopentanedicarboxylate
There total 6 articles about dimethyl (2R,3R,4S)-2,4-diacetoxy-3-benzyloxy-1,1-cyclopentanedicarboxylate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 80percent acetic acid / H2O / Heating
2: 1.) conc. HCl / 1.) -15 min, 30 min; 2.) pyridine, r.t., 13 h
3: mercury(II) chloride, calcium carbonate / acetonitrile; H2O / 0.5 h / Ambient temperature
4: pyridine; acetic anhydride / 36 h / Ambient temperature
5: sodium borohydride / methanol / 0.5 h / -15 °C
With
hydrogenchloride; sodium tetrahydroborate; acetic acid; calcium carbonate; mercury dichloride;
In
pyridine; methanol; water; acetic anhydride; acetonitrile;
DOI:10.1246/bcsj.60.3673
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) conc. HCl / 1.) -15 min, 30 min; 2.) pyridine, r.t., 13 h
2: mercury(II) chloride, calcium carbonate / acetonitrile; H2O / 0.5 h / Ambient temperature
3: pyridine; acetic anhydride / 36 h / Ambient temperature
4: sodium borohydride / methanol / 0.5 h / -15 °C
With
hydrogenchloride; sodium tetrahydroborate; calcium carbonate; mercury dichloride;
In
pyridine; methanol; water; acetic anhydride; acetonitrile;
DOI:10.1246/bcsj.60.3673
- Guidance literature:
-
Multi-step reaction with 3 steps
1: pyridine; acetic anhydride / 36 h / Ambient temperature
2: sodium borohydride / methanol / 0.5 h / -15 °C
With
sodium tetrahydroborate;
In
pyridine; methanol; acetic anhydride;
DOI:10.1246/bcsj.60.3673
