C₁₅H₂₂O₃

Base Information

• Chemical Name: C₁₅H₂₂O₃
• CAS No.: 176444-25-0
• Molecular Formula: C₁₅H₂₂O₃
• Molecular Weight: 250.338
• Mol file: 176444-25-0.mol

Synonyms:

Chemical Property of C₁₅H₂₂O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₅H₂₂O₃

There total 7 articles about C₁₅H₂₂O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(2R,3R,4S)-5-(benzyloxy)-3-methoxy-2,4-dimethylpentan-1-ol (1369677-32-6) → C15H22O3 (176444-25-0)

Guidance literature:

With oxalyl dichloride; dimethyl sulfoxide; triethylamine;

DOI:10.1016/j.tetlet.2012.02.049

Reference yield:

ethyl (4S)-5-(((tert-butyldiphenyl)silyl)oxy)-4-methyl-2(E)-pentenoate (133604-03-2) → C15H22O3 (176444-25-0)

Guidance literature:

Multi-step reaction with 7 steps

1: diisobutylaluminium hydride / diethyl ether

2: titanium(IV) isopropylate; tert.-butylhydroperoxide; diethyl (2S,3S)-tartrate

3: copper(l) iodide

4: sodium hydride / tetrahydrofuran

5: tetra-(n-butyl)ammonium iodide; sodium hydride / tetrahydrofuran

6: tetrabutyl ammonium fluoride / tetrahydrofuran

7: oxalyl dichloride; dimethyl sulfoxide; triethylamine

With titanium(IV) isopropylate; tert.-butylhydroperoxide; copper(l) iodide; oxalyl dichloride; diethyl (2S,3S)-tartrate; tetrabutyl ammonium fluoride; tetra-(n-butyl)ammonium iodide; sodium hydride; diisobutylaluminium hydride; dimethyl sulfoxide; triethylamine; In tetrahydrofuran; diethyl ether;

DOI:10.1016/j.tetlet.2012.02.049

Reference yield:

(4S)-5-(tert-butyldiphenylsilyloxy)-4-methyl-2-penten-1-ol (127665-68-3) → C15H22O3 (176444-25-0)

Guidance literature:

Multi-step reaction with 6 steps

1: titanium(IV) isopropylate; tert.-butylhydroperoxide; diethyl (2S,3S)-tartrate

2: copper(l) iodide

3: sodium hydride / tetrahydrofuran

4: tetra-(n-butyl)ammonium iodide; sodium hydride / tetrahydrofuran

5: tetrabutyl ammonium fluoride / tetrahydrofuran

6: oxalyl dichloride; dimethyl sulfoxide; triethylamine

With titanium(IV) isopropylate; tert.-butylhydroperoxide; copper(l) iodide; oxalyl dichloride; diethyl (2S,3S)-tartrate; tetrabutyl ammonium fluoride; tetra-(n-butyl)ammonium iodide; sodium hydride; dimethyl sulfoxide; triethylamine; In tetrahydrofuran;

DOI:10.1016/j.tetlet.2012.02.049

upstream raw materials:

(2R,3R,4S)-5-(benzyloxy)-3-methoxy-2,4-dimethylpentan-1-ol

(4S)-5-(tert-butyldiphenylsilyloxy)-4-methyl-2-penten-1-ol

((2R,3R)-3-((R)-1-((tert-butyldiphenylsilyl)oxy)propan-2-yl)oxiran-2-yl)methanol

(2S,3S,4R)-5-<(tert-butyl)diphenylsilyloxy>-2,4-dimethylpentane-1,3-diol

Downstream raw materials:

C₂₃H₃₀O₃

C₂₃H₃₀O₃

3,5-dimethoxy-2,4-dimethyl-7-phenyl-(2S,3S,4R,5S,6E)-6-hepten-1-ol

ethyl 7,9-dimethoxy-3,6,8-trimethyl-11-phenyl-(2E,4E,6S,7S,8R,9S,10E)-2,4,10-undecatrienoate