CIS-2-(3-CHLOROBENZOYL)CYCLOHEXANE-1-CARBOXYLIC ACID

Base Information

• Chemical Name: CIS-2-(3-CHLOROBENZOYL)CYCLOHEXANE-1-CARBOXYLIC ACID
• CAS No.: 357980-62-2
• Molecular Formula: C₁₄H₁₅ClO₃
• Molecular Weight: 266.724
• Mol file: 357980-62-2.mol

Synonyms:

Chemical Property of CIS-2-(3-CHLOROBENZOYL)CYCLOHEXANE-1-CARBOXYLIC ACID

Chemical Property:

• Vapor Pressure: 8.78E-09mmHg at 25°C
• Melting Point: 135-139
• Boiling Point: 447.2±40.0 °C(Predicted)
• PKA: 4.27±0.44(Predicted)
• Density: 1.284±0.06 g/cm3(Predicted)

Purity/Quality:

Cis-2-(3-chlorobenzoyl)cyclohexane-1-carboxylicacid 97% ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

Useful:

Technology Process of CIS-2-(3-CHLOROBENZOYL)CYCLOHEXANE-1-CARBOXYLIC ACID

There total 1 articles about CIS-2-(3-CHLOROBENZOYL)CYCLOHEXANE-1-CARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

1-bromo-3-chlorobenzene (108-37-2) + 1,2-cis-cyclohexanedicarboxylic anhydride (13149-00-3) → cis-2-(3-chlorobenzoyl)cyclohexanecarboxylic acid (357980-62-2)

Guidance literature:

1-bromo-3-chlorobenzene; With n-butyllithium; In tetrahydrofuran; hexane; at -80 ℃; for 0.25h;

1,2-cis-cyclohexanedicarboxylic anhydride; In tetrahydrofuran; hexane; at -80 ℃; for 2h; Further stages.;

DOI:10.1021/jm010838c

upstream raw materials:

1-bromo-3-chlorobenzene

1,2-cis-cyclohexanedicarboxylic anhydride

Refernces