Technology Process of C38H27F5N4
There total 12 articles about C38H27F5N4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium phosphate; tris-(dibenzylideneacetone)dipalladium(0); tri tert-butylphosphoniumtetrafluoroborate;
In
tetrahydrofuran; water;
at 20 ℃;
for 2.5h;
DOI:10.1016/j.bmcl.2014.05.082
- Guidance literature:
-
Multi-step reaction with 2 steps
1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / N,N-dimethyl-formamide / 14 h / 105 °C
2: potassium phosphate; tris-(dibenzylideneacetone)dipalladium(0); tri tert-butylphosphoniumtetrafluoroborate / tetrahydrofuran; water / 2.5 h / 20 °C
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium phosphate; tris-(dibenzylideneacetone)dipalladium(0); potassium acetate; tri tert-butylphosphoniumtetrafluoroborate;
In
tetrahydrofuran; water; N,N-dimethyl-formamide;
1: |Suzuki Coupling / 2: |Suzuki Coupling;
DOI:10.1016/j.bmcl.2014.05.082
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: sodium hydride / 1-methyl-pyrrolidin-2-one / 24 h / 120 °C
2.1: lithium chloride / dimethyl sulfoxide; water / 3 h / 165 °C
3.1: tetrabutylammomium bromide; sodium hydroxide / toluene; water / 16 h / 20 °C
4.1: copper(l) cyanide; TurboGrignard / tetrahydrofuran / 1 h / 0 - 20 °C
5.1: ozone / dichloromethane; methanol / 1 h / -78 °C
5.2: 16 h / -78 - 20 °C
6.1: diethylamino-sulfur trifluoride / dichloromethane / 2 h / -20 °C
7.1: potassium phosphate; tris-(dibenzylideneacetone)dipalladium(0); tri tert-butylphosphoniumtetrafluoroborate / tetrahydrofuran; water / 2.5 h / 20 °C
With
potassium phosphate; tris-(dibenzylideneacetone)dipalladium(0); TurboGrignard; diethylamino-sulfur trifluoride; tetrabutylammomium bromide; copper(l) cyanide; sodium hydride; ozone; lithium chloride; sodium hydroxide; tri tert-butylphosphoniumtetrafluoroborate;
In
tetrahydrofuran; 1-methyl-pyrrolidin-2-one; methanol; dichloromethane; water; dimethyl sulfoxide; toluene;
2.1: |Krapcho Dealkoxycarbonylation / 7.1: |Suzuki Coupling;
DOI:10.1016/j.bmcl.2014.05.082
