(R)-4-((3-((4-(2,2-diphenylacetamido)-5-(4-hydroxybenzylamino)-5-oxopentyl)guanidino)-3-oxopropyl)(methyl)amino)pyridinium 2,2,2-trifluoroacetate

Base Information

Chemical Name:(R)-4-((3-((4-(2,2-diphenylacetamido)-5-(4-hydroxybenzylamino)-5-oxopentyl)guanidino)-3-oxopropyl)(methyl)amino)pyridinium 2,2,2-trifluoroacetate
CAS No.:1365543-66-3
Molecular Formula:C₂HF₃O₂*C₃₆H₄₁N₇O₄
Molecular Weight:749.79
Hs Code.:

(R)-4-((3-((4-(2,2-diphenylacetamido)-5-(4-hydroxybenzylamino)-5-oxopentyl)guanidino)-3-oxopropyl)(methyl)amino)pyridinium 2,2,2-trifluoroacetate

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Chemical Property of (R)-4-((3-((4-(2,2-diphenylacetamido)-5-(4-hydroxybenzylamino)-5-oxopentyl)guanidino)-3-oxopropyl)(methyl)amino)pyridinium 2,2,2-trifluoroacetate

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Technology Process of (R)-4-((3-((4-(2,2-diphenylacetamido)-5-(4-hydroxybenzylamino)-5-oxopentyl)guanidino)-3-oxopropyl)(methyl)amino)pyridinium 2,2,2-trifluoroacetate

There total 4 articles about (R)-4-((3-((4-(2,2-diphenylacetamido)-5-(4-hydroxybenzylamino)-5-oxopentyl)guanidino)-3-oxopropyl)(methyl)amino)pyridinium 2,2,2-trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 193818-07-4
C₉H₁₂N₂O₂*ClH

: 1365543-66-3
(R)-4-((3-((4-(2,2-diphenylacetamido)-5-(4-hydroxybenzylamino)-5-oxopentyl)guanidino)-3-oxopropyl)(methyl)amino)pyridinium 2,2,2-trifluoroacetate

Guidance literature:: Multi-step reaction with 3 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 0.25 h

2: triethylamine; mercury dichloride / N,N-dimethyl-formamide

3: dichloromethane / 2 h

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; N-ethyl-N,N-diisopropylamine; mercury dichloride; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1135/cccc2011036

Reference yield:

: 1365267-06-6
C₁₆H₂₄N₄O₃S

: 1365543-66-3
(R)-4-((3-((4-(2,2-diphenylacetamido)-5-(4-hydroxybenzylamino)-5-oxopentyl)guanidino)-3-oxopropyl)(methyl)amino)pyridinium 2,2,2-trifluoroacetate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; mercury dichloride / N,N-dimethyl-formamide

2: dichloromethane / 2 h

With triethylamine; mercury dichloride; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1135/cccc2011036

Reference yield:

: 80028-34-8
methyl 3-propionate hydrochloride

: 1365543-66-3
(R)-4-((3-((4-(2,2-diphenylacetamido)-5-(4-hydroxybenzylamino)-5-oxopentyl)guanidino)-3-oxopropyl)(methyl)amino)pyridinium 2,2,2-trifluoroacetate

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hydroxide / methanol

2: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 0.25 h

3: triethylamine; mercury dichloride / N,N-dimethyl-formamide

4: dichloromethane / 2 h

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; N-ethyl-N,N-diisopropylamine; mercury dichloride; sodium hydroxide; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1135/cccc2011036