cyclohexyl-(1⁽²⁾H-tetrazol-5-yl)-amine

Base Information

• Chemical Name: cyclohexyl-(1⁽²⁾H-tetrazol-5-yl)-amine
• CAS No.: 14910-05-5
• Molecular Formula: C₇H₁₃N₅
• Molecular Weight: 167.214
• Mol file: 14910-05-5.mol

Synonyms:

Chemical Property of cyclohexyl-(1⁽²⁾H-tetrazol-5-yl)-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cyclohexyl-(1⁽²⁾H-tetrazol-5-yl)-amine

There total 3 articles about cyclohexyl-(1⁽²⁾H-tetrazol-5-yl)-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 12.0%

N-cyanocyclohexylamine (4421-48-1) → cyclohexyl-(1(2)H-tetrazol-5-yl)-amine (14910-05-5)

Guidance literature:

With trimethylsilylazide; In methanol; dichloromethane; for 2h; Schlenk technique; Inert atmosphere;

DOI:10.1002/chem.201803252

Reference yield:

→ cyclohexyl-(1(2)H-tetrazol-5-yl)-amine (14910-05-5)

Guidance literature:

With palladium; acetic acid; Hydrogenation;

DOI:10.1021/jo50013a002

Reference yield:

Cyclohexyl isocyanide (931-53-3) → cyclohexyl-(1(2)H-tetrazol-5-yl)-amine (14910-05-5)

Guidance literature:

Multi-step reaction with 2 steps

1: [Au(MeCN)(PPh₃)][SbF₆]; trimethylsilylazide / dichloromethane; methanol / 1 h / 20 °C / Schlenk technique; Inert atmosphere

2: trimethylsilylazide / dichloromethane; methanol / 2 h / Schlenk technique; Inert atmosphere

With trimethylsilylazide; [Au(MeCN)(PPh₃)][SbF₆]; In methanol; dichloromethane;

DOI:10.1002/chem.201803252

upstream raw materials:

Cyclohexyl isocyanide

N-cyanocyclohexylamine

Downstream raw materials:

1-(cyclohexyl)-1H-tetrazol-5-amine

Refernces