2-[2-(1H-INDOL-3-YL)ETHYL]-1,3(2H,4H)-ISOQUINOLINEDIONE

Base Information

• Chemical Name: 2-[2-(1H-INDOL-3-YL)ETHYL]-1,3(2H,4H)-ISOQUINOLINEDIONE
• CAS No.: 39662-65-2
• Molecular Formula: C₁₉H₁₆N₂O₂
• Molecular Weight: 304.348
• Mol file: 39662-65-2.mol

Synonyms:

Chemical Property of 2-[2-(1H-INDOL-3-YL)ETHYL]-1,3(2H,4H)-ISOQUINOLINEDIONE

Chemical Property:

• Melting Point: 205 °C
• Boiling Point: 591.2±50.0 °C(Predicted)
• PKA: 17.13±0.30(Predicted)
• Density: 1.317±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

2-[2-(1H-INDOL-3-YL)ETHYL]-1,3(2H,4H)-ISOQUINOLINEDIONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[2-(1H-INDOL-3-YL)ETHYL]-1,3(2H,4H)-ISOQUINOLINEDIONE

There total 4 articles about 2-[2-(1H-INDOL-3-YL)ETHYL]-1,3(2H,4H)-ISOQUINOLINEDIONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tryptamine (61-54-1) + Homophthalic acid (89-51-0) → 2-(2-indol-3-yl-ethyl)-4H-isoquinoline-1,3-dione (39662-65-2)

Guidance literature:

at 180 ℃;

DOI:10.1021/ja01173a041 DOI:10.1039/jr9460000617

Reference yield:

tryptamine (61-54-1) + homophthalic anhydride (703-59-3) → 2-(2-indol-3-yl-ethyl)-4H-isoquinoline-1,3-dione (39662-65-2)

Guidance literature:

With benzene; Erhitzen des Reaktionsprodukts unter vermindertem Druck;

DOI:10.1002/hlca.193501801123

Reference yield:

→ 2-(2-indol-3-yl-ethyl)-4H-isoquinoline-1,3-dione (39662-65-2)

Guidance literature:

at 185 ℃;

DOI:10.1039/jr9460000617

upstream raw materials:

tryptamine

Homophthalic acid

homophthalic anhydride