(+/-)-4,7-Dimethyl-<2.2>-paracyclophan

Base Information

• Chemical Name: (+/-)-4,7-Dimethyl-<2.2>-paracyclophan
• CAS No.: 32212-91-2
• Molecular Formula: C₁₈H₂₀
• Molecular Weight: 236.357
• Mol file: 32212-91-2.mol

Synonyms:

Chemical Property of (+/-)-4,7-Dimethyl-<2.2>-paracyclophan

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-4,7-Dimethyl-<2.2>-paracyclophan

There total 12 articles about (+/-)-4,7-Dimethyl-<2.2>-paracyclophan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

15-Bromomethyl-5-methyl-tricyclo[8.2.2.24,7]hexadeca-1(13),4(16),5,7(15),10(14),11-hexaene (36325-23-2) → (+/-)-4,7-Dimethyl-<2.2>-paracyclophan (35117-18-1,36325-21-0,32212-91-2)

Guidance literature:

With lithium aluminium tetrahydride;

DOI:10.1021/ja00365a060

Reference yield:

(R)-(-)-4-Hydroxymethyl-7-methyl[2.2]paracyclophan (36325-22-1) → (+/-)-4,7-Dimethyl-<2.2>-paracyclophan (35117-18-1,36325-21-0,32212-91-2)

Guidance literature:

Multi-step reaction with 2 steps

1: PBr₃ / CH₂Cl₂

2: LiAlH₄ / tetrahydrofuran

With lithium aluminium tetrahydride; phosphorus tribromide; In tetrahydrofuran; dichloromethane;

DOI:10.1002/hlca.19810640704

Reference yield:

[2.2]Paracyclophan (1633-22-3) → (+/-)-4,7-Dimethyl-<2.2>-paracyclophan (35117-18-1,36325-21-0,32212-91-2)

Guidance literature:

Multi-step reaction with 8 steps

1: TiCl₄

2: LiAlH₄

3: PBr₃ / CH₂Cl₂

4: LiAlH₄ / tetrahydrofuran

5: TiCl₄

6: LiAlH₄

7: PBr₃ / CH₂Cl₂

8: LiAlH₄ / tetrahydrofuran

With lithium aluminium tetrahydride; phosphorus tribromide; titanium tetrachloride; In tetrahydrofuran; dichloromethane;

DOI:10.1002/hlca.19810640704

upstream raw materials:

(4-methylbenzyl)-trimethylammonium chloride

15-Bromomethyl-5-methyl-tricyclo[8.2.2.2^4,7]hexadeca-1⁽¹³⁾,4⁽¹⁶⁾,5,7⁽¹⁵⁾,10⁽¹⁴⁾,11-hexaene

(4-methylbenzyl)trimethylammonium bromide

trimethyl-(2,4,5-trimethyl-benzyl)-ammonium; bromide

Downstream raw materials:

4,7,13,16-tetramethyl[2.2]paracyclophane