p-Chlor-β-propyl-hydrozimtsaeure

Base Information

• Chemical Name: p-Chlor-β-propyl-hydrozimtsaeure
• CAS No.: 15954-51-5
• Molecular Formula: C₁₂H₁₅ClO₂
• Molecular Weight: 226.703
• Mol file: 15954-51-5.mol

Synonyms:

Chemical Property of p-Chlor-β-propyl-hydrozimtsaeure

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of p-Chlor-β-propyl-hydrozimtsaeure

There total 4 articles about p-Chlor-β-propyl-hydrozimtsaeure which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(4-chlorophenyl)butan-1-ol (13856-86-5) → p-Chlor-β-propyl-hydrozimtsaeure (15954-51-5)

Guidance literature:

Multi-step reaction with 3 steps

1: PBr₃, Py / diethyl ether

2: NaOEt / ethanol

3: (i) aq. KOH, EtOH, (ii) (decarboxylation)

With pyridine; sodium ethanolate; phosphorus tribromide; In diethyl ether; ethanol;

DOI:10.1135/cccc19760633

Reference yield:

1-Brom-1-(4-chlorphenyl)-butan (59771-07-2) → p-Chlor-β-propyl-hydrozimtsaeure (15954-51-5)

Guidance literature:

Multi-step reaction with 2 steps

1: NaOEt / ethanol

2: (i) aq. KOH, EtOH, (ii) (decarboxylation)

With sodium ethanolate; In ethanol;

DOI:10.1135/cccc19760633

Reference yield:

1,1-Dichloroethylene (75-35-4,9002-85-1) + 1-(4-chlorophenyl)butan-1-ol (13856-86-5) → p-Chlor-β-propyl-hydrozimtsaeure (15954-51-5)

Guidance literature:

With sulfuric acid; boron trifluoride;

upstream raw materials:

1,1-Dichloroethylene

1-(4-chlorophenyl)butan-1-ol

Diethyl-1-(4-chlorphenyl)-butylmalonat

1-Brom-1-(4-chlorphenyl)-butan