Technology Process of (2S,3R,4R)-2-<(2R)-2-(benzoyloxy)tetracosanoylamino>-3,4-dibenzoyloxy-1-hexadecanol
There total 6 articles about (2S,3R,4R)-2-<(2R)-2-(benzoyloxy)tetracosanoylamino>-3,4-dibenzoyloxy-1-hexadecanol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
toluene-4-sulfonic acid;
In
methanol; chloroform;
for 10h;
Yield given;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: DCC, HOBt, N-ethylmorpholine / tetrahydrofuran / 20 h / Ambient temperature
2: 83 percent / BF3*OEt2, Me2S / CH2Cl2 / 1 h / Ambient temperature
3: 1) DMAP, pyridine / 1) 65 deg C, 2.5h, 2) RT, 12h
4: p-TsOH*H2O / methanol; CHCl3 / 10 h / Ambient temperature
With
N-ethylmorpholine;; pyridine; dmap; dimethylsulfide; boron trifluoride diethyl etherate; benzotriazol-1-ol; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide;
In
tetrahydrofuran; methanol; dichloromethane; chloroform;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: DCC, HOBt, N-ethylmorpholine / tetrahydrofuran / 20 h / Ambient temperature
2: 83 percent / BF3*OEt2, Me2S / CH2Cl2 / 1 h / Ambient temperature
3: 1) DMAP, pyridine / 1) 65 deg C, 2.5h, 2) RT, 12h
4: p-TsOH*H2O / methanol; CHCl3 / 10 h / Ambient temperature
With
N-ethylmorpholine;; pyridine; dmap; dimethylsulfide; boron trifluoride diethyl etherate; benzotriazol-1-ol; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide;
In
tetrahydrofuran; methanol; dichloromethane; chloroform;
