NPS-Sarcolysin

Base Information

• Chemical Name: NPS-Sarcolysin
• CAS No.: 23583-14-4
• Molecular Formula: C₁₉H₂₁Cl₂N₃O₄S
• Molecular Weight: 458.365
• Mol file: 23583-14-4.mol

Synonyms:

Chemical Property of NPS-Sarcolysin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of NPS-Sarcolysin

There total 1 articles about NPS-Sarcolysin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

melphalan (531-76-0,8057-25-8) + 2-nitrobenzenesulfenyl chloride (7669-54-7) → NPS-Sarcolysin (23583-14-4)

Guidance literature:

With sodium hydroxide;

DOI:10.1007/BF00908178

Reference yield:

NPS-Sarcolysin (23583-14-4) → Sarc-β-Ala-OEt (47503-12-8)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N, DCC

2: H₂ / Pd

With hydrogen; triethylamine; dicyclohexyl-carbodiimide; palladium;

DOI:10.1007/BF00908178

Reference yield:

NPS-Sarcolysin (23583-14-4) → Sarc-Gly (23578-99-6)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N, DCC

2: aq. HCO₂H

With formic acid; triethylamine; dicyclohexyl-carbodiimide;

DOI:10.1007/BF00908178

upstream raw materials:

melphalan

2-nitrobenzenesulfenyl chloride

Downstream raw materials:

NPS-Sarc-β-Ala-OEt

NPS-Sarc-α-Ala-OBzh

NPS-Sarc-Gly-OBzh

Sarc-Gly