Technology Process of 1,22-Bis(3-brom-4,5-dimethoxyphenyl)docosan
There total 6 articles about 1,22-Bis(3-brom-4,5-dimethoxyphenyl)docosan which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 54 percent / Na / methanol / 8 h / 20 - 30 °C / electrolysis
2: 91.5 percent / dimethylformamide / 24 h / Heating
3: 15percent n-BuLi / diethyl ether; tetrahydrofuran; hexane / 0.5 h / 0 °C
4: 2.) H2 / 2.) Pd/C / 1.) ether, THF, hexane, 2 h, r.t., 2.) THF, r.t., 30 min
With
n-butyllithium; hydrogen; sodium;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; diethyl ether; hexane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 91.5 percent / dimethylformamide / 24 h / Heating
2: 15percent n-BuLi / diethyl ether; tetrahydrofuran; hexane / 0.5 h / 0 °C
3: 2.) H2 / 2.) Pd/C / 1.) ether, THF, hexane, 2 h, r.t., 2.) THF, r.t., 30 min
With
n-butyllithium; hydrogen;
palladium on activated charcoal;
In
tetrahydrofuran; diethyl ether; hexane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 86 percent / K2CO3 / dimethylformamide / 12 h / Ambient temperature
2: 2.) H2 / 2.) Pd/C / 1.) ether, THF, hexane, 2 h, r.t., 2.) THF, r.t., 30 min
With
hydrogen; potassium carbonate;
palladium on activated charcoal;
In
N,N-dimethyl-formamide;
