(R)-4-phenylbutan-2-yl acetate

Base Information

Chemical Name:(R)-4-phenylbutan-2-yl acetate
CAS No.:59960-25-7
Molecular Formula:C₁₂H₁₆O₂
Molecular Weight:192.258
Hs Code.:

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-4-phenylbutan-2-yl acetate

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Technology Process of (R)-4-phenylbutan-2-yl acetate

There total 24 articles about (R)-4-phenylbutan-2-yl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 2344-70-9
1-phenyl-3-butanol

: 581-55-5
benzylidene 1,1-diacetate

: 10415-88-0,59960-25-7,109431-71-2,129098-41-5
(R)-4-phenylbutan-2-yl acetate

Guidance literature:: With dicarbonyl(chloro)(η⁵-pentaphenylcyclopentadienyl)ruthenium(II); potassium tert-butylate; C_. antarctica B immobilized lipase; sodium carbonate; In tetrahydrofuran; toluene; at 60 ℃; for 3h; stereoselective reaction; Schlenk technique; Inert atmosphere; Enzymatic reaction;
DOI:10.1021/acs.joc.1c00154

Reference yield: 96.0%

: 108-22-5
Isopropenyl acetate

: 2344-70-9
1-phenyl-3-butanol

: 10415-88-0,59960-25-7,109431-71-2,129098-41-5
(R)-4-phenylbutan-2-yl acetate

Guidance literature:: With dicarbonylchlorido(pentabenzylcyclopentadienyl)ruthenium; potassium tert-butylate; sodium carbonate; In tetrahydrofuran; toluene; at 23 ℃; for 3h; optical yield given as %ee; enantioselective reaction; Inert atmosphere; dynamic kinetic resolution; Enzymatic reaction;
DOI:10.1002/ejoc.201001703

Reference yield: 87.0%

: 108-22-5
Isopropenyl acetate

: 2550-26-7
4-Phenyl-2-butanone

: (S)-4-phenyl-2-butyl acetate

: 10415-88-0,59960-25-7,109431-71-2,129098-41-5
(R)-4-phenylbutan-2-yl acetate

Guidance literature:: 4-Phenyl-2-butanone; With C₅₁H₄₁P₂Ru⁽¹⁺⁾*C₃₂H₁₂BF₂₄^(1-); potassium carbonate; In isopropyl alcohol; toluene; at 70 ℃; for 1h; Glovebox;

Isopropenyl acetate; With Candida antarctica lipase B; C₅₁H₄₁P₂Ru⁽¹⁺⁾*C₃₂H₁₂BF₂₄^(1-); In toluene; at 20 ℃; for 16h; enantioselective reaction;
DOI:10.1002/chem.201404096