Technology Process of (E,Z)-2-<(4-methylphenyl)methylene>-3-(2-thienylmethylene)succinic anhydride
There total 4 articles about (E,Z)-2-<(4-methylphenyl)methylene>-3-(2-thienylmethylene)succinic anhydride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: t-BuOK / 2-methyl-propan-2-ol / 0.75 h / Heating
2: 95 percent / K2CO3 / acetone / Heating
3: EtONa / diethyl ether / 48 h / -15 - -10 °C
4: Ac2O / 2 h / Heating
With
potassium tert-butylate; sodium ethanolate; acetic anhydride; potassium carbonate;
In
diethyl ether; acetone; tert-butyl alcohol;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: EtONa / diethyl ether / 48 h / -15 - -10 °C
2: Ac2O / 2 h / Heating
With
sodium ethanolate; acetic anhydride;
In
diethyl ether;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 95 percent / K2CO3 / acetone / Heating
2: EtONa / diethyl ether / 48 h / -15 - -10 °C
3: Ac2O / 2 h / Heating
With
sodium ethanolate; acetic anhydride; potassium carbonate;
In
diethyl ether; acetone;
