C₄₂H₄₄N₂O₁₉

Base Information

• Chemical Name: C₄₂H₄₄N₂O₁₉
• CAS No.: 748745-97-3
• Molecular Formula: C₄₂H₄₄N₂O₁₉
• Molecular Weight: 880.813
• Mol file: 748745-97-3.mol

Synonyms:

Chemical Property of C₄₂H₄₄N₂O₁₉

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₂H₄₄N₂O₁₉

There total 9 articles about C₄₂H₄₄N₂O₁₉ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 2,3,4-tri-O-acetyl-D-glucopyranuronate (72692-06-9,73464-50-3,3082-95-9) → C42H44N2O19 (748745-97-3)

Guidance literature:

Multi-step reaction with 4 steps

1: Et₃N / toluene / 65 °C

2: CF₃COOH / CH₂Cl₂

3: 1.) BOP-Cl, EtN(i-Pr)2; 2.) EtN(i-Pr)2 / 1.) CH₂Cl₂; 2.) CH₂Cl₂

4: 1.) LiOH; 2.) cation exchange H⁽¹⁺⁾ form / 1.) MeOH, H₂O, 0 deg C

With lithium hydroxide; cation exchange H⁽¹⁺⁾ form; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane; toluene;

DOI:10.1016/0040-4039(95)00049-I

Reference yield:

homophthalic anhydride (703-59-3) → C42H44N2O19 (748745-97-3)

Guidance literature:

Multi-step reaction with 8 steps

1: DMAP

2: H₂SO₄ / CH₂Cl₂

3: Pd(PPh₃)4, morpholine / tetrahydrofuran

4: (PhO)2P(O)N₃, Et₃N / toluene / 65 °C

5: Et₃N / toluene / 65 °C

6: CF₃COOH / CH₂Cl₂

7: 1.) BOP-Cl, EtN(i-Pr)2; 2.) EtN(i-Pr)2 / 1.) CH₂Cl₂; 2.) CH₂Cl₂

8: 1.) LiOH; 2.) cation exchange H⁽¹⁺⁾ form / 1.) MeOH, H₂O, 0 deg C

With morpholine; dmap; lithium hydroxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; cation exchange H⁽¹⁺⁾ form; sulfuric acid; diphenyl phosphoryl azide; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; toluene;

DOI:10.1016/0040-4039(95)00049-I

Reference yield:

2-Carboxymethyl-benzoic acid tert-butyl ester (168072-81-9) → C42H44N2O19 (748745-97-3)

Guidance literature:

Multi-step reaction with 5 steps

1: (PhO)2P(O)N₃, Et₃N / toluene / 65 °C

2: Et₃N / toluene / 65 °C

3: CF₃COOH / CH₂Cl₂

4: 1.) BOP-Cl, EtN(i-Pr)2; 2.) EtN(i-Pr)2 / 1.) CH₂Cl₂; 2.) CH₂Cl₂

5: 1.) LiOH; 2.) cation exchange H⁽¹⁺⁾ form / 1.) MeOH, H₂O, 0 deg C

With lithium hydroxide; cation exchange H⁽¹⁺⁾ form; diphenyl phosphoryl azide; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane; toluene;

DOI:10.1016/0040-4039(95)00049-I

upstream raw materials:

C₄₉H₅₂N₂O₂₂

methyl 2,3,4-tri-O-acetyl-D-glucopyranuronate

homophthalic anhydride

2-Carboxymethyl-benzoic acid tert-butyl ester