(+/-)-δ-elemene

Base Information

• Chemical Name: (+/-)-δ-elemene
• CAS No.: 80796-88-9
• Molecular Formula: C₁₅H₂₄
• Molecular Weight: 204.356
• Mol file: 80796-88-9.mol

Synonyms:

Chemical Property of (+/-)-δ-elemene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-δ-elemene

There total 14 articles about (+/-)-δ-elemene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.0%

elemol (639-99-6) → (3S,4aR,7aR)-1,3,3a,4,7,7a-hexahydro-6-isopropyl-1,1,3,3a-tetramethylsiobenzofuran + (S)-6-ethenyl-6-methyl-1-(1-methylethyl)-3-(1-methylethylidene)cyclohexene (5951-67-7) + δ-elemene (80796-88-9) + β-cyperone (23665-63-6)

Guidance literature:

With perchloric acid; In acetic acid; at 25 - 27 ℃; for 72h;

DOI:10.1002/hlca.200690050

Reference yield:

2-methyl-2-(4-methyl-3-pentenyl)-1,3-dioxolane (3695-38-3) → (+/-)-δ-elemene (1206-34-4,20307-84-0,80796-88-9)

Guidance literature:

Multi-step reaction with 11 steps

2: Collin's reagent

3: NaH / bis-(2-methoxy-ethyl) ether

4: LiAlH₄

5: 80 percent / Collin's reagent

7: 85 percent / dil. HCl / acetone

9: LiAlH₄

10: PBr₃

11: Ni(CO)4 / dimethylformamide

With hydrogenchloride; lithium aluminium tetrahydride; phosphorus tribromide; dipyridine chromium trioxide; sodium hydride; tetracarbonyl nickel; In diethylene glycol dimethyl ether; N,N-dimethyl-formamide; acetone;

Reference yield:

6,6-ethylenedioxy-2-methyl-hept-3-ol (89654-11-5) → (+/-)-δ-elemene (1206-34-4,20307-84-0,80796-88-9)

Guidance literature:

Multi-step reaction with 10 steps

1: Collin's reagent

2: NaH / bis-(2-methoxy-ethyl) ether

3: LiAlH₄

4: 80 percent / Collin's reagent

6: 85 percent / dil. HCl / acetone

8: LiAlH₄

9: PBr₃

10: Ni(CO)4 / dimethylformamide

With hydrogenchloride; lithium aluminium tetrahydride; phosphorus tribromide; dipyridine chromium trioxide; sodium hydride; tetracarbonyl nickel; In diethylene glycol dimethyl ether; N,N-dimethyl-formamide; acetone;

upstream raw materials:

2-(4-nitro-benzoyloxy)-2-((1R)-4c-methyl-4t-vinyl-3c-isopropenyl-cyclohexyl-(r))-propane

elemol

germacrene C

2-methyl-2-(4-methyl-3-pentenyl)-1,3-dioxolane

Downstream raw materials:

4t-ethyl-3r-isopropenyl-1-isopropyl-4c-methyl-cyclohexene

1-((1R,2R)-2-Ethyl-5-isopropyl-2-methyl-cyclohexyl)-ethanone

Refernces

• 1、 Wahidulla, Solimabi,Govenkar, Mangala Babu,Paknikar, Sashikumar Keshav. "Reaction of elemol with acetic acid/perchloric acid: Characterization of a novel oxide and (+)-β-cyperone". . p. 496 - 501. Retrieved 2007/10/03.
• 2、 Morikawa,Hirose. "Germacrene-C, precursor of delta-elemene.". . p. 1799 - 1801. Retrieved 2007/10/15.