Technology Process of γ-linolenic acid
There total 4 articles about γ-linolenic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 99 percent / H2, quinoline / Lindlar's catalyst / petroleum ether
2: sodium iodide / acetone / 33 h / Heating
3: 2.) sodium hydroxide / 1.) toluene, reflux, 5.5 h, 2.) ethanol, water, 80 deg C, 2 h, 3.) 150 deg C, 1 h
With
quinoline; sodium hydroxide; hydrogen; sodium iodide;
Lindlar's catalyst;
In
acetone; Petroleum ether;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 82.7 percent / lithium chloride / dimethylformamide / 1 h / 150 °C
2: 99 percent / H2, quinoline / Lindlar's catalyst / petroleum ether
3: sodium iodide / acetone / 33 h / Heating
4: 2.) sodium hydroxide / 1.) toluene, reflux, 5.5 h, 2.) ethanol, water, 80 deg C, 2 h, 3.) 150 deg C, 1 h
With
quinoline; sodium hydroxide; hydrogen; sodium iodide; lithium chloride;
Lindlar's catalyst;
In
N,N-dimethyl-formamide; acetone; Petroleum ether;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium iodide / acetone / 33 h / Heating
2: 2.) sodium hydroxide / 1.) toluene, reflux, 5.5 h, 2.) ethanol, water, 80 deg C, 2 h, 3.) 150 deg C, 1 h
With
sodium hydroxide; sodium iodide;
In
acetone;