(4S,5R,6R)-5-Benzyloxy-2-((2R,3R,4S,6R)-4,6-dimethoxy-3-methyl-tetrahydro-pyran-2-yl)-4-methyl-6-((4S,5S)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-hept-1-en-3-ol

Base Information

Chemical Name:(4S,5R,6R)-5-Benzyloxy-2-((2R,3R,4S,6R)-4,6-dimethoxy-3-methyl-tetrahydro-pyran-2-yl)-4-methyl-6-((4S,5S)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-hept-1-en-3-ol
CAS No.:79391-41-6
Molecular Formula:C₂₉H₄₆O₇
Molecular Weight:506.68
Hs Code.:

(4S,5R,6R)-5-Benzyloxy-2-((2R,3R,4S,6R)-4,6-dimethoxy-3-methyl-tetrahydro-pyran-2-yl)-4-methyl-6-((4S,5S)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-hept-1-en-3-ol

Synonyms:

Suppliers and Price of (4S,5R,6R)-5-Benzyloxy-2-((2R,3R,4S,6R)-4,6-dimethoxy-3-methyl-tetrahydro-pyran-2-yl)-4-methyl-6-((4S,5S)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-hept-1-en-3-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4S,5R,6R)-5-Benzyloxy-2-((2R,3R,4S,6R)-4,6-dimethoxy-3-methyl-tetrahydro-pyran-2-yl)-4-methyl-6-((4S,5S)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-hept-1-en-3-ol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4S,5R,6R)-5-Benzyloxy-2-((2R,3R,4S,6R)-4,6-dimethoxy-3-methyl-tetrahydro-pyran-2-yl)-4-methyl-6-((4S,5S)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-hept-1-en-3-ol

There total 10 articles about (4S,5R,6R)-5-Benzyloxy-2-((2R,3R,4S,6R)-4,6-dimethoxy-3-methyl-tetrahydro-pyran-2-yl)-4-methyl-6-((4S,5S)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-hept-1-en-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 79386-76-8,84278-12-6
2-O-benzyl-1,4,7-trideoxy-5,6-O-isopropylidene-4-C-methyl-L-glycero-D-talo-heptitol

: 79391-41-6,79464-41-8
(4S,5R,6R)-5-Benzyloxy-2-((2R,3R,4S,6R)-4,6-dimethoxy-3-methyl-tetrahydro-pyran-2-yl)-4-methyl-6-((4S,5S)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-hept-1-en-3-ol

Guidance literature:: Multi-step reaction with 8 steps

1: 96 percent / DMAP / ethyl acetate / 1.5 h / Ambient temperature

2: H₂ / palladium black / methanol / 0.17 h / Ambient temperature

3: pyridine / 1 h / Ambient temperature

4: 958 mg / CH₃ONa / CHCl₃; methanol / 20 h / 0 °C

5: 1.) BuLi / 1.) THF, hexane, -20 deg C, 2 h, 2.) THF, hexane, -20 deg C, 2 h, then 0-2 deg C, 4 d

6: 1.) NaH / 1.) DMF, RT, 0.5 h, 2.) DMF, RT, 0.5 h

7: HgO, HgCl₂ / acetone; H₂O / 0.33 h / 70 °C

8: 1.) BuLi / 1.) ether, hexane, -78 deg C, 1.5 h, 2.) ether, hexane, -78 to 0 deg C, 1.5 h

With pyridine; dmap; n-butyllithium; hydrogen; sodium methylate; sodium hydride; mercury dichloride; mercury(II) oxide; palladium; In methanol; chloroform; water; ethyl acetate; acetone;
DOI:10.1246/bcsj.54.1749

Reference yield:

: 121408-87-5,121408-88-6,121408-91-1,121408-92-2
5-O-Benzyl-3,6-dideoxy-3-C-methyl-D-altrofuranose

: 79391-41-6,79464-41-8
(4S,5R,6R)-5-Benzyloxy-2-((2R,3R,4S,6R)-4,6-dimethoxy-3-methyl-tetrahydro-pyran-2-yl)-4-methyl-6-((4S,5S)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-hept-1-en-3-ol

Guidance literature:: Multi-step reaction with 10 steps

1: 72 percent / diethyl ether / 20 h / Heating

2: 93 percent / p-TsOH / dimethylformamide / 0.5 h / Ambient temperature

3: 96 percent / DMAP / ethyl acetate / 1.5 h / Ambient temperature

4: H₂ / palladium black / methanol / 0.17 h / Ambient temperature

5: pyridine / 1 h / Ambient temperature

6: 958 mg / CH₃ONa / CHCl₃; methanol / 20 h / 0 °C

7: 1.) BuLi / 1.) THF, hexane, -20 deg C, 2 h, 2.) THF, hexane, -20 deg C, 2 h, then 0-2 deg C, 4 d

8: 1.) NaH / 1.) DMF, RT, 0.5 h, 2.) DMF, RT, 0.5 h

9: HgO, HgCl₂ / acetone; H₂O / 0.33 h / 70 °C

10: 1.) BuLi / 1.) ether, hexane, -78 deg C, 1.5 h, 2.) ether, hexane, -78 to 0 deg C, 1.5 h

With pyridine; dmap; n-butyllithium; hydrogen; sodium methylate; sodium hydride; toluene-4-sulfonic acid; mercury dichloride; mercury(II) oxide; palladium; In methanol; diethyl ether; chloroform; water; ethyl acetate; N,N-dimethyl-formamide; acetone;
DOI:10.1246/bcsj.54.1749

Reference yield:

: 79386-79-1,84278-13-7
3-O-acetyl-2-O-benzyl-1,4,7-trideoxy-5,6-O-isopropylidene-4-C-methyl-L-glycero-D-talo-heptitol

: 79391-41-6,79464-41-8
(4S,5R,6R)-5-Benzyloxy-2-((2R,3R,4S,6R)-4,6-dimethoxy-3-methyl-tetrahydro-pyran-2-yl)-4-methyl-6-((4S,5S)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-hept-1-en-3-ol

Guidance literature:: Multi-step reaction with 7 steps

1: H₂ / palladium black / methanol / 0.17 h / Ambient temperature

2: pyridine / 1 h / Ambient temperature

3: 958 mg / CH₃ONa / CHCl₃; methanol / 20 h / 0 °C

4: 1.) BuLi / 1.) THF, hexane, -20 deg C, 2 h, 2.) THF, hexane, -20 deg C, 2 h, then 0-2 deg C, 4 d

5: 1.) NaH / 1.) DMF, RT, 0.5 h, 2.) DMF, RT, 0.5 h

6: HgO, HgCl₂ / acetone; H₂O / 0.33 h / 70 °C

7: 1.) BuLi / 1.) ether, hexane, -78 deg C, 1.5 h, 2.) ether, hexane, -78 to 0 deg C, 1.5 h

With pyridine; n-butyllithium; hydrogen; sodium methylate; sodium hydride; mercury dichloride; mercury(II) oxide; palladium; In methanol; chloroform; water; acetone;
DOI:10.1246/bcsj.54.1749