(R)-2-Methyl-2-triethylsilanyloxy-succinic acid 1-benzyl ester 4-{(R)-1-[(R)-methoxy-(methoxy-methyl-carbamoyl)-methyl]-2-methyl-propyl} ester

Base Information

Chemical Name:(R)-2-Methyl-2-triethylsilanyloxy-succinic acid 1-benzyl ester 4-{(R)-1-[(R)-methoxy-(methoxy-methyl-carbamoyl)-methyl]-2-methyl-propyl} ester
CAS No.:568578-55-2
Molecular Formula:C₂₇H₄₅NO₈Si
Molecular Weight:539.742
Hs Code.:

(R)-2-Methyl-2-triethylsilanyloxy-succinic acid 1-benzyl ester 4-{(R)-1-[(R)-methoxy-(methoxy-methyl-carbamoyl)-methyl]-2-methyl-propyl} ester

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Chemical Property of (R)-2-Methyl-2-triethylsilanyloxy-succinic acid 1-benzyl ester 4-{(R)-1-[(R)-methoxy-(methoxy-methyl-carbamoyl)-methyl]-2-methyl-propyl} ester

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Technology Process of (R)-2-Methyl-2-triethylsilanyloxy-succinic acid 1-benzyl ester 4-{(R)-1-[(R)-methoxy-(methoxy-methyl-carbamoyl)-methyl]-2-methyl-propyl} ester

There total 5 articles about (R)-2-Methyl-2-triethylsilanyloxy-succinic acid 1-benzyl ester 4-{(R)-1-[(R)-methoxy-(methoxy-methyl-carbamoyl)-methyl]-2-methyl-propyl} ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 18854-19-8
benzyl pyruvate

: 568578-55-2
(R)-2-Methyl-2-triethylsilanyloxy-succinic acid 1-benzyl ester 4-{(R)-1-[(R)-methoxy-(methoxy-methyl-carbamoyl)-methyl]-2-methyl-propyl} ester

Guidance literature:: Multi-step reaction with 5 steps

1: LDA

2: lutidine

3: aq. LiOH

4: Ph₂P(O)Cl; Et₃N

With lithium hydroxide; lutidine; triethylamine; lithium diisopropyl amide; Diphenylphosphinic chloride; 1: Evans' Aldol reaction;
DOI:10.1016/S0960-894X(03)00105-7

Reference yield:

: 568578-53-0
(R)-2-Methyl-2-triethylsilanyloxy-succinic acid 1-benzyl ester

: 568578-55-2
(R)-2-Methyl-2-triethylsilanyloxy-succinic acid 1-benzyl ester 4-{(R)-1-[(R)-methoxy-(methoxy-methyl-carbamoyl)-methyl]-2-methyl-propyl} ester

Guidance literature:: Multi-step reaction with 2 steps

1: Ph₂P(O)Cl; Et₃N

With triethylamine; Diphenylphosphinic chloride;
DOI:10.1016/S0960-894X(03)00105-7

Reference yield:

: 568578-51-8
(R)-4-((R)-4-Benzyl-2-oxo-oxazolidin-3-yl)-2-hydroxy-2-methyl-4-oxo-butyric acid benzyl ester

: 568578-55-2
(R)-2-Methyl-2-triethylsilanyloxy-succinic acid 1-benzyl ester 4-{(R)-1-[(R)-methoxy-(methoxy-methyl-carbamoyl)-methyl]-2-methyl-propyl} ester

Guidance literature:: Multi-step reaction with 4 steps

1: lutidine

2: aq. LiOH

3: Ph₂P(O)Cl; Et₃N

With lithium hydroxide; lutidine; triethylamine; Diphenylphosphinic chloride;
DOI:10.1016/S0960-894X(03)00105-7