C₅₈H₇₅F₆N₈O₁₅PSi

Base Information

• Chemical Name: C₅₈H₇₅F₆N₈O₁₅PSi
• CAS No.: 646506-17-4
• Molecular Formula: C₅₈H₇₅F₆N₈O₁₅PSi
• Molecular Weight: 1297.33
• Mol file: 646506-17-4.mol

Synonyms:

Chemical Property of C₅₈H₇₅F₆N₈O₁₅PSi

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₈H₇₅F₆N₈O₁₅PSi

There total 4 articles about C₅₈H₇₅F₆N₈O₁₅PSi which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2,2-trifluoro-N-[2-({2-[(trifluoroacetyl)amino]ethyl}amino)ethyl]acetamide (88793-42-4) → C58H75F6N8O15PSi (646506-17-4)

Guidance literature:

Multi-step reaction with 4 steps

1: 50 percent / triethylamine / acetonitrile / 24 h / Heating

2: 70 percent / triphenylphosphine; lithium azide; CCl₄ / dimethylformamide / 2 h / 20 °C

3: H₂ / Pd/C / methanol

4: pyridine / acetonitrile; CCl₄ / 0.17 h

With pyridine; tetrachloromethane; lithium azide; hydrogen; triethylamine; triphenylphosphine; palladium on activated charcoal; In methanol; tetrachloromethane; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1016/S0968-0896(03)00273-6

Reference yield:

N-(2-{(3-azido-propyl)-[2-(2,2,2-trifluoro-acetylamino)-ethyl]-amino}-ethyl)-2,2,2-trifluoro-acetamide (646506-05-0) → C58H75F6N8O15PSi (646506-17-4)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / Pd/C / methanol

2: pyridine / acetonitrile; CCl₄ / 0.17 h

With pyridine; hydrogen; palladium on activated charcoal; In methanol; tetrachloromethane; acetonitrile;

DOI:10.1016/S0968-0896(03)00273-6

Reference yield:

2,2,2-trifluoro-N-(2-{(3-hydroxy-propyl)-[2-(2,2,2-trifluoro-acetylamino)-ethyl]-amino}-ethyl)-acetamide (646506-03-8) → C58H75F6N8O15PSi (646506-17-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 70 percent / triphenylphosphine; lithium azide; CCl₄ / dimethylformamide / 2 h / 20 °C

2: H₂ / Pd/C / methanol

3: pyridine / acetonitrile; CCl₄ / 0.17 h

With pyridine; tetrachloromethane; lithium azide; hydrogen; triphenylphosphine; palladium on activated charcoal; In methanol; tetrachloromethane; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1016/S0968-0896(03)00273-6

upstream raw materials:

(S_P)-5'-O-(4,4-dimethoxytrityl)-2'-thymidylyl-(3'->5')-3'-O-<1,1-dimethylethyl)dimethylsilyl>-thymidine 3'-H-phosphonate

N-(2-{(3-amino-propyl)-[2-(2,2,2-trifluoro-acetylamino)-ethyl]-amino}-ethyl)-2,2,2-trifluoro-acetamide

2,2,2-trifluoro-N-[2-({2-[(trifluoroacetyl)amino]ethyl}amino)ethyl]acetamide

2,2,2-trifluoro-N-(2-{(3-hydroxy-propyl)-[2-(2,2,2-trifluoro-acetylamino)-ethyl]-amino}-ethyl)-acetamide

Downstream raw materials:

C₅₂H₆₁F₆N₈O₁₅P