(4Z,7Z,10Z,13Z,16Z,19Z)-Docosa-4,7,10,13,16,19-hexaenoic acid (S)-1-hydroxymethyl-2-octadecanoyloxy-ethyl ester

Base Information

Chemical Name:(4Z,7Z,10Z,13Z,16Z,19Z)-Docosa-4,7,10,13,16,19-hexaenoic acid (S)-1-hydroxymethyl-2-octadecanoyloxy-ethyl ester
CAS No.:65886-80-8
Molecular Formula:C₄₃H₇₂O₅
Molecular Weight:669.042
Hs Code.:

Synonyms:

Suppliers and Price of (4Z,7Z,10Z,13Z,16Z,19Z)-Docosa-4,7,10,13,16,19-hexaenoic acid (S)-1-hydroxymethyl-2-octadecanoyloxy-ethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4Z,7Z,10Z,13Z,16Z,19Z)-Docosa-4,7,10,13,16,19-hexaenoic acid (S)-1-hydroxymethyl-2-octadecanoyloxy-ethyl ester

Chemical Property:

Purity/Quality:

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Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of (4Z,7Z,10Z,13Z,16Z,19Z)-Docosa-4,7,10,13,16,19-hexaenoic acid (S)-1-hydroxymethyl-2-octadecanoyloxy-ethyl ester

There total 4 articles about (4Z,7Z,10Z,13Z,16Z,19Z)-Docosa-4,7,10,13,16,19-hexaenoic acid (S)-1-hydroxymethyl-2-octadecanoyloxy-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 111-63-7,9003-95-6
vinyl stearate

: 65886-80-8
(4Z,7Z,10Z,13Z,16Z,19Z)-Docosa-4,7,10,13,16,19-hexaenoic acid (S)-1-hydroxymethyl-2-octadecanoyloxy-ethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: lipase / propan-2-ol

2: 1.) POCl₃, 3.) H₂O, 4.) H₂ / 4.) Pd(OH)2/C / 1.) Et₃N, 2.) pyridine, 4.) H₂O, Ch₃OH

3: DCC, DMAP / CHCl₃

4: phosphalipase C, CaCl₂, sodium deoxycholate, Tris-HCl buffer, pH 7.5

With dmap; Tris-HCl buffer; sodium salt of choleic acid; phosphalipase C; water; hydrogen; dicyclohexyl-carbodiimide; calcium chloride; lipase; trichlorophosphate; palladium dihydroxide; In chloroform; isopropyl alcohol;
DOI:10.1271/bbb.60.1916

Reference yield:

: 85647-89-8
(S)-1-stearoyl-2-O-benzyl-sn-glycerol

: 65886-80-8
(4Z,7Z,10Z,13Z,16Z,19Z)-Docosa-4,7,10,13,16,19-hexaenoic acid (S)-1-hydroxymethyl-2-octadecanoyloxy-ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) POCl₃, 3.) H₂O, 4.) H₂ / 4.) Pd(OH)2/C / 1.) Et₃N, 2.) pyridine, 4.) H₂O, Ch₃OH

2: DCC, DMAP / CHCl₃

3: phosphalipase C, CaCl₂, sodium deoxycholate, Tris-HCl buffer, pH 7.5

With dmap; Tris-HCl buffer; sodium salt of choleic acid; phosphalipase C; water; hydrogen; dicyclohexyl-carbodiimide; calcium chloride; trichlorophosphate; palladium dihydroxide; In chloroform;
DOI:10.1271/bbb.60.1916

Reference yield:

: 171597-35-6
1-stearoyl-2-benzylglycerophosphocholine

: 65886-80-8
(4Z,7Z,10Z,13Z,16Z,19Z)-Docosa-4,7,10,13,16,19-hexaenoic acid (S)-1-hydroxymethyl-2-octadecanoyloxy-ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: DCC, DMAP / CHCl₃

2: phosphalipase C, CaCl₂, sodium deoxycholate, Tris-HCl buffer, pH 7.5

With dmap; Tris-HCl buffer; sodium salt of choleic acid; phosphalipase C; dicyclohexyl-carbodiimide; calcium chloride; In chloroform;
DOI:10.1271/bbb.60.1916