1-Hydroxydodecan-2-one

Base Information

Chemical Name:1-Hydroxydodecan-2-one
CAS No.:139199-56-7
Molecular Formula:C12H24O2
Molecular Weight:200.321
Hs Code.:
DSSTox Substance ID:DTXSID90567410
Nikkaji Number:J2.722.223D
Wikidata:Q82453296

Synonyms:139199-56-7;n-dodeconol;1-hydroxydodecan-2-one;SCHEMBL14917739;DTXSID90567410

Suppliers and Price of 1-Hydroxydodecan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 1-Hydroxydodecan-2-one

Chemical Property:

PSA：37.30000
LogP:3.07860
XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:10
Exact Mass:200.177630004
Heavy Atom Count:14
Complexity:132

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCCCCCC(=O)CO

Technology Process of 1-Hydroxydodecan-2-one

There total 2 articles about 1-Hydroxydodecan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 6.5%

: 112-41-4,25067-08-7,62132-67-6
1-dodecene

: 1119-87-5
dodecane-1,2-diol

: 139199-56-7
1-hydroxyl-2-dodecanone

: 112-44-7
undecylaldehyde

: 2,4-di-n-decyl-1,3-dioxolane

Guidance literature:: With ruthenium tetroxide; In water; acetone; at -70 ℃; for 0.166667h; Further byproducts given;

Reference yield:

: 1119-87-5
dodecane-1,2-diol

: 139199-56-7
1-hydroxyl-2-dodecanone

: 112-44-7
undecylaldehyde

Guidance literature:: With dihydrogen peroxide; C₁₁H₁₈Br₂FeN₄⁽¹⁺⁾*Br^(1-); In acetonitrile; at 30 ℃; for 24h;
DOI:10.1002/ejoc.202001201

Reference yield:

: 139199-56-7
1-hydroxyl-2-dodecanone

: C₂₀H₃₃NO

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran / 2 h / 0 - 20 °C / Inert atmosphere

2: pyridine / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere

3: [1,2-bis-(phenylsulfinyl)ethane]palladium(II) acetate; bis[2-(diphenylphosphino)phenyl] ether / N,N-dimethyl-formamide / 12 h / 20 °C

With pyridine; [1,2-bis-(phenylsulfinyl)ethane]palladium(II) acetate; bis[2-(diphenylphosphino)phenyl] ether; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jacs.6b07382