C₂₃H₂₆N₂O₄

Base Information

• Chemical Name: C₂₃H₂₆N₂O₄
• CAS No.: 1477811-55-4
• Molecular Formula: C₂₃H₂₆N₂O₄
• Molecular Weight: 394.47
• Mol file: 1477811-55-4.mol

Synonyms:

Chemical Property of C₂₃H₂₆N₂O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₃H₂₆N₂O₄

There total 5 articles about C₂₃H₂₆N₂O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid (53-86-1) → C23H26N2O4 (1477811-55-4)

Guidance literature:

Multi-step reaction with 5 steps

1.1: 4-methyl-morpholine / tetrahydrofuran / 0.17 h / -10 °C

1.2: 0.5 h

2.1: ammonium hydroxide / tetrahydrofuran / 3 h / 20 °C

3.1: sodium hydroxide / tetrahydrofuran

4.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 °C

4.2: 20 °C

5.1: potassium carbonate / acetonitrile / 12 h / Reflux

With 4-methyl-morpholine; ammonium hydroxide; sodium hydride; potassium carbonate; sodium hydroxide; In tetrahydrofuran; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1002/cjoc.201300079

Reference yield:

2-(5-methoxy-2-methyl-1H-indol-3-yl)acetamide (15992-10-6) → C23H26N2O4 (1477811-55-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 °C

1.2: 20 °C

2.1: potassium carbonate / acetonitrile / 12 h / Reflux

With sodium hydride; potassium carbonate; In N,N-dimethyl-formamide; acetonitrile;

DOI:10.1002/cjoc.201300079

Reference yield:

Indomethacin amide (6264-33-1) → C23H26N2O4 (1477811-55-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium hydroxide / tetrahydrofuran

2.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 °C

2.2: 20 °C

3.1: potassium carbonate / acetonitrile / 12 h / Reflux

With sodium hydride; potassium carbonate; sodium hydroxide; In tetrahydrofuran; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1002/cjoc.201300079

upstream raw materials:

[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid

2-(1-(4-chlorobutyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetamide

meta-hydroxybenzaldehyde

2-(5-methoxy-2-methyl-1H-indol-3-yl)acetamide

Downstream raw materials:

2-(1-(4-(3-(cyano(phenylamino)methyl)phenoxy)butyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetamide