(R,S)-N-(2,6-dimethylphenyl)piperidinium-2-carboxamide bis-(trifluoromethylsulfonyl)imide

Base Information

• Chemical Name: (R,S)-N-(2,6-dimethylphenyl)piperidinium-2-carboxamide bis-(trifluoromethylsulfonyl)imide
• CAS No.: 1364698-38-3
• Molecular Formula: C₂HF₆NO₄S₂*C₁₄H₂₀N₂O
• Molecular Weight: 513.482
• Mol file: 1364698-38-3.mol

Synonyms:

Chemical Property of (R,S)-N-(2,6-dimethylphenyl)piperidinium-2-carboxamide bis-(trifluoromethylsulfonyl)imide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R,S)-N-(2,6-dimethylphenyl)piperidinium-2-carboxamide bis-(trifluoromethylsulfonyl)imide

There total 1 articles about (R,S)-N-(2,6-dimethylphenyl)piperidinium-2-carboxamide bis-(trifluoromethylsulfonyl)imide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2',6'-pipecoloxylidide (15883-20-2,27262-40-4,27262-43-7,78341-12-5) + bis(trifluoromethanesulfonyl)amide (82113-65-3) → (R,S)-N-(2,6-dimethylphenyl)piperidinium-2-carboxamide bis-(trifluoromethylsulfonyl)imide (1364698-38-3)

Guidance literature:

In acetonitrile; for 0.5h;

DOI:10.1039/c2cc17799d

Reference yield:

(R,S)-N-(2,6-dimethylphenyl)piperidinium-2-carboxamide bis-(trifluoromethylsulfonyl)imide (1364698-38-3) + C4H5O6(1-)*C16H36P(1+) → tetrabutylphosphonium bis(trifluoromethanesulfonyl)imide + C4H6O6*C14H20N2O + C2HF6NO4S2*C14H20N2O

Guidance literature:

(R,S)-N-(2,6-dimethylphenyl)piperidinium-2-carboxamide bis-(trifluoromethylsulfonyl)imide; C₄H₅O₆^(1-)*C₁₆H₃₆P⁽¹⁺⁾; at 50 ℃; for 2h; Ionic liquid; Resolution of racemate;

In water; at 20 ℃; for 12h; optical yield given as %ee; Resolution of racemate;

DOI:10.1039/c2cc17799d

Reference yield:

(R,S)-N-(2,6-dimethylphenyl)piperidinium-2-carboxamide bis-(trifluoromethylsulfonyl)imide (1364698-38-3) + C4H4O6(2-)*2C16H36P(1+) → tetrabutylphosphonium bis(trifluoromethanesulfonyl)imide + C4H6O6*2C14H20N2O + C2HF6NO4S2*C14H20N2O

Guidance literature:

(R,S)-N-(2,6-dimethylphenyl)piperidinium-2-carboxamide bis-(trifluoromethylsulfonyl)imide; C₄H₄O₆^(2-)*2C₁₆H₃₆P⁽¹⁺⁾; at 50 ℃; for 2h; Ionic liquid; Resolution of racemate;

In water; at 20 ℃; for 12h; Resolution of racemate;

DOI:10.1039/c2cc17799d

upstream raw materials:

2',6'-pipecoloxylidide

bis(trifluoromethanesulfonyl)amide

Refernces